Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage

Huifeng Yue; Lin Guo; Xiangqian Liu; Magnus Rueping

doi:10.1021/acs.orglett.7b00556

Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage

Huifeng Yue, Lin Guo, Xiangqian Liu, Magnus Rueping

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.

Original language	English (US)
Pages (from-to)	1788-1791
Number of pages	4
Journal	Organic Letters
Volume	19
Issue number	7
DOIs	https://doi.org/10.1021/acs.orglett.7b00556
State	Published - Mar 13 2017

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: H.Y., L.G., and X.L. were supported by the China Scholarship Council. Financial support by KAUST is gratefully acknowledged.

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10.1021/acs.orglett.7b00556

https://repository.kaust.edu.sa/bitstream/10754/623870/1/Manuscript%20accepted.pdf

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abstract = "A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.",

author = "Huifeng Yue and Lin Guo and Xiangqian Liu and Magnus Rueping",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: H.Y., L.G., and X.L. were supported by the China Scholarship Council. Financial support by KAUST is gratefully acknowledged.",

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T1 - Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage

AU - Yue, Huifeng

AU - Guo, Lin

AU - Liu, Xiangqian

AU - Rueping, Magnus

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: H.Y., L.G., and X.L. were supported by the China Scholarship Council. Financial support by KAUST is gratefully acknowledged.

PY - 2017/3/13

Y1 - 2017/3/13

N2 - A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.

AB - A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.

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EP - 1791

JO - Organic Letters

JF - Organic Letters

IS - 7

ER -

Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage

Abstract

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