Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage

Huifeng Yue, Lin Guo, Xiangqian Liu, Magnus Rueping

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35 Scopus citations


A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.
Original languageEnglish (US)
Pages (from-to)1788-1791
Number of pages4
JournalOrganic Letters
Issue number7
StatePublished - Mar 13 2017

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