Nickel-Catalyzed Csp2–Csp3 Bond Formation via C–F Bond Activation

Yee Ann Ho; Matthias Leiendecker; Xiangqian Liu; Chengming Wang; Nurtalya Alandini; Magnus Rueping

doi:10.1021/acs.orglett.8b02351

Nickel-Catalyzed Csp2–Csp3 Bond Formation via C–F Bond Activation

Yee Ann Ho, Matthias Leiendecker, Xiangqian Liu, Chengming Wang, Nurtalya Alandini, Magnus Rueping

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

A nickel-catalyzed cross coupling of aryl fluorides via C–F bond activation has been developed. The alkylation method allows selective replacement of aryl fluorides by alkyl groups and enables the synthesis of diverse and otherwise difficult to access scaffolds in good yields.

Original language	English (US)
Pages (from-to)	5644-5647
Number of pages	4
Journal	Organic Letters
Volume	20
Issue number	18
DOIs	https://doi.org/10.1021/acs.orglett.8b02351
State	Published - Aug 31 2018

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: Y.A.H. acknowledges the DAAD for a scholarship. M.L. was supported by a Kekulé fellowship (Fonds der Chemischen Industrie) and the Studienstiftung des Deutschen Volkes.

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10.1021/acs.orglett.8b02351

https://repository.kaust.edu.sa/bitstream/10754/628342/1/Manuscript.pdf

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title = "Nickel-Catalyzed Csp2–Csp3 Bond Formation via C–F Bond Activation",

abstract = "A nickel-catalyzed cross coupling of aryl fluorides via C–F bond activation has been developed. The alkylation method allows selective replacement of aryl fluorides by alkyl groups and enables the synthesis of diverse and otherwise difficult to access scaffolds in good yields.",

author = "Ho, {Yee Ann} and Matthias Leiendecker and Xiangqian Liu and Chengming Wang and Nurtalya Alandini and Magnus Rueping",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: Y.A.H. acknowledges the DAAD for a scholarship. M.L. was supported by a Kekul{\'e} fellowship (Fonds der Chemischen Industrie) and the Studienstiftung des Deutschen Volkes.",

year = "2018",

month = aug,

day = "31",

doi = "10.1021/acs.orglett.8b02351",

language = "English (US)",

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journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

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T1 - Nickel-Catalyzed Csp2–Csp3 Bond Formation via C–F Bond Activation

AU - Ho, Yee Ann

AU - Leiendecker, Matthias

AU - Liu, Xiangqian

AU - Wang, Chengming

AU - Alandini, Nurtalya

AU - Rueping, Magnus

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: Y.A.H. acknowledges the DAAD for a scholarship. M.L. was supported by a Kekulé fellowship (Fonds der Chemischen Industrie) and the Studienstiftung des Deutschen Volkes.

PY - 2018/8/31

Y1 - 2018/8/31

N2 - A nickel-catalyzed cross coupling of aryl fluorides via C–F bond activation has been developed. The alkylation method allows selective replacement of aryl fluorides by alkyl groups and enables the synthesis of diverse and otherwise difficult to access scaffolds in good yields.

AB - A nickel-catalyzed cross coupling of aryl fluorides via C–F bond activation has been developed. The alkylation method allows selective replacement of aryl fluorides by alkyl groups and enables the synthesis of diverse and otherwise difficult to access scaffolds in good yields.

UR - http://hdl.handle.net/10754/628342

UR - https://pubs.acs.org/doi/10.1021/acs.orglett.8b02351

UR - http://www.scopus.com/inward/record.url?scp=85052875765&partnerID=8YFLogxK

U2 - 10.1021/acs.orglett.8b02351

DO - 10.1021/acs.orglett.8b02351

M3 - Article

SN - 1523-7060

VL - 20

SP - 5644

EP - 5647

JO - Organic Letters

JF - Organic Letters

IS - 18

ER -

Nickel-Catalyzed Csp2–Csp3 Bond Formation via C–F Bond Activation

Abstract

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