Abstract
A nickel catalyzed cross-coupling protocol for the straightforward C−S bond formation has been developed. Various mercaptans and a wide range of ester and amide substrates bearing various substituents were tolerated in this process which afforded products in good to excellent yields. Furthermore, an intramolecular protocol for the synthesis of thioethers starting from thioesters has been developed. The utility of this protocol has been demonstrated in a new synthetic protocol of benzothiophene.
Original language | English (US) |
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Pages (from-to) | 3608-3612 |
Number of pages | 5 |
Journal | Chemistry - A European Journal |
Volume | 24 |
Issue number | 14 |
DOIs | |
State | Published - Mar 7 2018 |
Bibliographical note
Publisher Copyright:© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Keywords
- aryl amides
- aryl esters
- decarbonylation
- nickel catalysis
- thioesters
ASJC Scopus subject areas
- Catalysis
- General Chemistry
- Organic Chemistry