Nickel-Catalyzed Carbon-Selenium Bond Formations under Mild Conditions

Serik Zhumagazy; Chen Zhu; Huifeng Yue; Magnus Rueping

doi:10.1055/s-0042-1752655

Nickel-Catalyzed Carbon-Selenium Bond Formations under Mild Conditions

Serik Zhumagazy, Chen Zhu, Huifeng Yue^*, Magnus Rueping^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A nickel-catalyzed C-Se cross-coupling between aryl iodides and selenols is described. The newly developed catalytic methodology offers facile access to various unsymmetrical selenium-containing motifs. The reaction features excellent functional group tolerance, wide substrate scope, good efficiency, and operates under mild reaction conditions. Notably, this protocol could be readily scaled up to gram scale without the loss of yield.

Original language	English (US)
Pages (from-to)	1381-1384
Number of pages	4
Journal	Synlett
Volume	34
Issue number	12
DOIs	https://doi.org/10.1055/s-0042-1752655
State	Published - Jan 22 2023

Bibliographical note

Publisher Copyright:
© 2023 Georg Thieme Verlag. All rights reserved.

Keywords

aryl halide
C-Se bond formation
cross-coupling
nickel catalysis

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-0042-1752655

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abstract = "A nickel-catalyzed C-Se cross-coupling between aryl iodides and selenols is described. The newly developed catalytic methodology offers facile access to various unsymmetrical selenium-containing motifs. The reaction features excellent functional group tolerance, wide substrate scope, good efficiency, and operates under mild reaction conditions. Notably, this protocol could be readily scaled up to gram scale without the loss of yield.",

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AU - Zhumagazy, Serik

AU - Zhu, Chen

AU - Yue, Huifeng

AU - Rueping, Magnus

PY - 2023/1/22

Y1 - 2023/1/22

N2 - A nickel-catalyzed C-Se cross-coupling between aryl iodides and selenols is described. The newly developed catalytic methodology offers facile access to various unsymmetrical selenium-containing motifs. The reaction features excellent functional group tolerance, wide substrate scope, good efficiency, and operates under mild reaction conditions. Notably, this protocol could be readily scaled up to gram scale without the loss of yield.

AB - A nickel-catalyzed C-Se cross-coupling between aryl iodides and selenols is described. The newly developed catalytic methodology offers facile access to various unsymmetrical selenium-containing motifs. The reaction features excellent functional group tolerance, wide substrate scope, good efficiency, and operates under mild reaction conditions. Notably, this protocol could be readily scaled up to gram scale without the loss of yield.

KW - aryl halide

KW - C-Se bond formation

KW - cross-coupling

KW - nickel catalysis

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DO - 10.1055/s-0042-1752655

M3 - Article

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ER -

Nickel-Catalyzed Carbon-Selenium Bond Formations under Mild Conditions

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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