This report explores Suzuki-Miyaura coupling under microwave irradiation, using a new generation of catalyst that is based on natural phosphate (NP) impregnated by palladium. This catalyst was prepared by the treatment of natural phosphate with bis(benzonitrile)palladium(II) chloride in acetone at room temperature. The catalyst displayed high catalytic activity for the Suzuki-Miyaura coupling of aryl bromides and chlorides with aryl boronic acids in pure water and with the use of microwave irradiation. The low-cost and availability of the solid support, mild reaction conditions, high yields of desired products, recyclability of the catalyst and short reaction times are the notable features of these methods.
Bibliographical noteKAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We thank G. Santini for his support of this work and the Region Picardie for their financial support. The financial assistance of the Office Cherifien des Phosphates in the Moroccan Kingdom (OCP Group) towards this research is hereby acknowledged. This work was supported also by grant from the OCP Foundation.
ASJC Scopus subject areas
- Organic Chemistry