Nanoporous Polymeric Grating-Based Biosensors

Tieyu Gao, Vincent Hsiao, Yue Bing Zheng, Tony Jun Huang

Research output: Chapter in Book/Report/Conference proceedingConference contribution


We demonstrate the utilization of an interferometrically created nanoporous polymeric gratings as a platform for biosensing applications. Aminopropyltriethoxysilane (APTES)-functionalized nanoporous polymeric gratings was fabricated by combining holographic interference patterning and APTES-functionalization of pre-polymer syrup. The successful detection of multiple biomolecules indicates that the biofunctionalized nanoporous polymeric gratings can act as biosensing platforms which are label-free, inexpensive, and applicable as high-throughput assays. Copyright © 2010 by ASME.
Original languageEnglish (US)
Title of host publicationVolume 5: Energy Systems Analysis, Thermodynamics and Sustainability; NanoEngineering for Energy; Engineering to Address Climate Change, Parts A and B
PublisherASME International
Number of pages4
ISBN (Print)9780791844298
StatePublished - Apr 30 2012
Externally publishedYes

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: This research was supported by the Air Force Office of Scientific Research, the National Science Foundation, US Department of Agriculture (USDA/NRI), and the Penn State Center for Nanoscale Science (MRSEC). Components of this work were conducted at the Pennsylvania State University node of the NSF-funded National Nanotechnology Infrastructure Network. Y. B. Z. recognizes the support from KAUST Scholar Award and the Founder’s Prize and Grant of the American Academy of Mechanics. The authors thank Dr. Jinjie Shi, Mr. Brian Kiraly, and Dr. Xiaole Mao for helpful discussions.
This publication acknowledges KAUST support, but has no KAUST affiliated authors.


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