Nanoplasmonic and Microfluidic Devices for Biological Sensing

G. Perozziello; Andrea Giugni; Marco Allione; Bruno Torre; Gobind Das; M. L. Coluccio; Monica Marini; Luca Tirinato; Manola Moretti; Tania Limongi; P. Candeloro; Enzo M. Di Fabrizio

doi:10.1007/978-94-024-0850-8_12

Nanoplasmonic and Microfluidic Devices for Biological Sensing

G. Perozziello, Andrea Giugni, Marco Allione, Bruno Torre, Gobind Das, M. L. Coluccio, Monica Marini, Luca Tirinato, Manola Moretti, Tania Limongi, P. Candeloro, Enzo M. Di Fabrizio

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

In this chapter we report about recent advances on the development and application of 2D and 3D plasmonic nanostructures used for sensing of biological samples by Raman spectroscopy at unprecedented resolution of analysis. Besides, we explain how the integration of these nanodevices in a microfluidic apparatus can simplify the analysis of biological samples. In the first part we introduce and motivate the convenience of using nanoplasmonic enhancers and Raman spectroscopy for biological sensing, describing the phenomena and the current approaches to fabricate nanoplasmonic structures. In the second part, we explain how specific multi-element devices produce the optimal enhancement of the Raman scattering. We report cases where biological sensing of DNA was performed at few molecules level with nanometer spatial resolutions. Finally, we show an example of microfluidic device integrating plasmonic nanodevices to sort and drive biological samples, like living cells, towards the optical probe in order to obtain optimal conditions of analysis.

Original language	English (US)
Title of host publication	NATO Science for Peace and Security Series B: Physics and Biophysics
Publisher	Springer Nature
Pages	247-274
Number of pages	28
ISBN (Print)	9789402408485
DOIs	https://doi.org/10.1007/978-94-024-0850-8_12
State	Published - Feb 17 2017

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We acknowledge all contributors that contributed in this work from other institution, in particular the researchers from the previous Nanostructure Division at IIT (Italian Institute of Technology) in Genoa. We thank for the financial support the King Abdullah University of Science and Technology start-up fund and the Italian Minister of Health (projects nos. GR-2010-2320665 and GR-2010-2311677)

ASJC Scopus subject areas

Biophysics
Biotechnology
Electrical and Electronic Engineering
General Physics and Astronomy

Access to Document

10.1007/978-94-024-0850-8_12

https://repository.kaust.edu.sa/bitstream/10754/623189/1/Nano%20optics%20Erice_chap.12.pdf

Cite this

Perozziello, G., Giugni, A., Allione, M., Torre, B., Das, G., Coluccio, M. L., Marini, M., Tirinato, L., Moretti, M., Limongi, T., Candeloro, P., & Di Fabrizio, E. M. (2017). Nanoplasmonic and Microfluidic Devices for Biological Sensing. In NATO Science for Peace and Security Series B: Physics and Biophysics (pp. 247-274). Springer Nature. https://doi.org/10.1007/978-94-024-0850-8_12

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abstract = "In this chapter we report about recent advances on the development and application of 2D and 3D plasmonic nanostructures used for sensing of biological samples by Raman spectroscopy at unprecedented resolution of analysis. Besides, we explain how the integration of these nanodevices in a microfluidic apparatus can simplify the analysis of biological samples. In the first part we introduce and motivate the convenience of using nanoplasmonic enhancers and Raman spectroscopy for biological sensing, describing the phenomena and the current approaches to fabricate nanoplasmonic structures. In the second part, we explain how specific multi-element devices produce the optimal enhancement of the Raman scattering. We report cases where biological sensing of DNA was performed at few molecules level with nanometer spatial resolutions. Finally, we show an example of microfluidic device integrating plasmonic nanodevices to sort and drive biological samples, like living cells, towards the optical probe in order to obtain optimal conditions of analysis.",

author = "G. Perozziello and Andrea Giugni and Marco Allione and Bruno Torre and Gobind Das and Coluccio, {M. L.} and Monica Marini and Luca Tirinato and Manola Moretti and Tania Limongi and P. Candeloro and {Di Fabrizio}, {Enzo M.}",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: We acknowledge all contributors that contributed in this work from other institution, in particular the researchers from the previous Nanostructure Division at IIT (Italian Institute of Technology) in Genoa. We thank for the financial support the King Abdullah University of Science and Technology start-up fund and the Italian Minister of Health (projects nos. GR-2010-2320665 and GR-2010-2311677)",

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doi = "10.1007/978-94-024-0850-8_12",

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T1 - Nanoplasmonic and Microfluidic Devices for Biological Sensing

AU - Perozziello, G.

AU - Giugni, Andrea

AU - Allione, Marco

AU - Torre, Bruno

AU - Das, Gobind

AU - Coluccio, M. L.

AU - Marini, Monica

AU - Tirinato, Luca

AU - Moretti, Manola

AU - Limongi, Tania

AU - Candeloro, P.

AU - Di Fabrizio, Enzo M.

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: We acknowledge all contributors that contributed in this work from other institution, in particular the researchers from the previous Nanostructure Division at IIT (Italian Institute of Technology) in Genoa. We thank for the financial support the King Abdullah University of Science and Technology start-up fund and the Italian Minister of Health (projects nos. GR-2010-2320665 and GR-2010-2311677)

PY - 2017/2/17

Y1 - 2017/2/17

N2 - In this chapter we report about recent advances on the development and application of 2D and 3D plasmonic nanostructures used for sensing of biological samples by Raman spectroscopy at unprecedented resolution of analysis. Besides, we explain how the integration of these nanodevices in a microfluidic apparatus can simplify the analysis of biological samples. In the first part we introduce and motivate the convenience of using nanoplasmonic enhancers and Raman spectroscopy for biological sensing, describing the phenomena and the current approaches to fabricate nanoplasmonic structures. In the second part, we explain how specific multi-element devices produce the optimal enhancement of the Raman scattering. We report cases where biological sensing of DNA was performed at few molecules level with nanometer spatial resolutions. Finally, we show an example of microfluidic device integrating plasmonic nanodevices to sort and drive biological samples, like living cells, towards the optical probe in order to obtain optimal conditions of analysis.

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BT - NATO Science for Peace and Security Series B: Physics and Biophysics

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ER -

Nanoplasmonic and Microfluidic Devices for Biological Sensing

Abstract

Bibliographical note

ASJC Scopus subject areas

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