Nano-particles for biomedical applications

Paolo Decuzzi; Alessandro Coclite; Aeju Lee; Anna Lisa Palange; Daniele Di Mascolo; Ciro Chiappini; Hélder A. Santos; Maria Laura Coluccio; Gerardo Perozziello; Patrizio Candeloro; Enzo M. Di Fabrizio; Francesco Gentile

doi:10.1007/978-3-662-54357-3_21

Nano-particles for biomedical applications

Paolo Decuzzi, Alessandro Coclite, Aeju Lee, Anna Lisa Palange, Daniele Di Mascolo, Ciro Chiappini, Hélder A. Santos, Maria Laura Coluccio, Gerardo Perozziello, Patrizio Candeloro, Enzo M. Di Fabrizio, Francesco Gentile

Research output: Chapter in Book/Report/Conference proceeding › Chapter

7 Scopus citations

Abstract

Nanoparticles (NPnanoparticle (NP)s) are extremely small particulates with an average size that ranges from a micron or less to a few nanometers. The large majority of NPs necessitate nanotechnology methods for their production. The size of NPs may vary over a significant range, which underlies their scientific potential in that NPs may help cross the bridge between bulk materials and molecular structures. More importantly, NPs are (nano)tech products and thus, in contrast to natural systems, they can be designed and engineered. On directly interacting with cells, including the structures of cells, their machinery and their waste products, NPs represent an unprecedented tool for addressing specific biological problems. In this chapter, we will briefly review some recent advances in nanoparticle research for biomedical applications, ranging from mesoporous silicon particles to gold and silver nanoparticles and polymeric nanocarriers for therapeutic, diagnosis, or theranostic (therapeutics + diagnosis) applications. We will offer a description of how, at the current state of the art, similar nanomedicine platforms are realized.

Original language	English (US)
Title of host publication	Springer Handbook of Nanotechnology
Publisher	Springer Berlin Heidelberg
Pages	643-691
Number of pages	49
ISBN (Print)	9783662543559
DOIs	https://doi.org/10.1007/978-3-662-54357-3_21
State	Published - Nov 6 2017

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: Dr. Hélder A. Santos acknowledges the Academy of Finland (project numbers 252215 and 281300), the University of Helsinki and the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013)/ERC Grant agreement number 310892 for financial support. Dr. Dongfei Liu and Dr. Bárbara Herranz Blanco (Division of Pharmaceutical Chemistry and Technology) are also acknowledged for their discussions and for providing some of the material in the microfluidics section. Professor Francesco Gentile acknowledges the Italian Minister of Health (Project number GR-2010-2320665).

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title = "Nano-particles for biomedical applications",

abstract = "Nanoparticles (NPnanoparticle (NP)s) are extremely small particulates with an average size that ranges from a micron or less to a few nanometers. The large majority of NPs necessitate nanotechnology methods for their production. The size of NPs may vary over a significant range, which underlies their scientific potential in that NPs may help cross the bridge between bulk materials and molecular structures. More importantly, NPs are (nano)tech products and thus, in contrast to natural systems, they can be designed and engineered. On directly interacting with cells, including the structures of cells, their machinery and their waste products, NPs represent an unprecedented tool for addressing specific biological problems. In this chapter, we will briefly review some recent advances in nanoparticle research for biomedical applications, ranging from mesoporous silicon particles to gold and silver nanoparticles and polymeric nanocarriers for therapeutic, diagnosis, or theranostic (therapeutics + diagnosis) applications. We will offer a description of how, at the current state of the art, similar nanomedicine platforms are realized.",

author = "Paolo Decuzzi and Alessandro Coclite and Aeju Lee and Palange, {Anna Lisa} and {Di Mascolo}, Daniele and Ciro Chiappini and Santos, {H{\'e}lder A.} and Coluccio, {Maria Laura} and Gerardo Perozziello and Patrizio Candeloro and {Di Fabrizio}, {Enzo M.} and Francesco Gentile",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: Dr. H{\'e}lder A. Santos acknowledges the Academy of Finland (project numbers 252215 and 281300), the University of Helsinki and the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013)/ERC Grant agreement number 310892 for financial support. Dr. Dongfei Liu and Dr. B{\'a}rbara Herranz Blanco (Division of Pharmaceutical Chemistry and Technology) are also acknowledged for their discussions and for providing some of the material in the microfluidics section. Professor Francesco Gentile acknowledges the Italian Minister of Health (Project number GR-2010-2320665).",

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doi = "10.1007/978-3-662-54357-3_21",

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AU - Decuzzi, Paolo

AU - Coclite, Alessandro

AU - Lee, Aeju

AU - Palange, Anna Lisa

AU - Di Mascolo, Daniele

AU - Chiappini, Ciro

AU - Santos, Hélder A.

AU - Coluccio, Maria Laura

AU - Perozziello, Gerardo

AU - Candeloro, Patrizio

AU - Di Fabrizio, Enzo M.

AU - Gentile, Francesco

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: Dr. Hélder A. Santos acknowledges the Academy of Finland (project numbers 252215 and 281300), the University of Helsinki and the European Research Council under the European Union's Seventh Framework Programme (FP7/2007-2013)/ERC Grant agreement number 310892 for financial support. Dr. Dongfei Liu and Dr. Bárbara Herranz Blanco (Division of Pharmaceutical Chemistry and Technology) are also acknowledged for their discussions and for providing some of the material in the microfluidics section. Professor Francesco Gentile acknowledges the Italian Minister of Health (Project number GR-2010-2320665).

PY - 2017/11/6

Y1 - 2017/11/6

N2 - Nanoparticles (NPnanoparticle (NP)s) are extremely small particulates with an average size that ranges from a micron or less to a few nanometers. The large majority of NPs necessitate nanotechnology methods for their production. The size of NPs may vary over a significant range, which underlies their scientific potential in that NPs may help cross the bridge between bulk materials and molecular structures. More importantly, NPs are (nano)tech products and thus, in contrast to natural systems, they can be designed and engineered. On directly interacting with cells, including the structures of cells, their machinery and their waste products, NPs represent an unprecedented tool for addressing specific biological problems. In this chapter, we will briefly review some recent advances in nanoparticle research for biomedical applications, ranging from mesoporous silicon particles to gold and silver nanoparticles and polymeric nanocarriers for therapeutic, diagnosis, or theranostic (therapeutics + diagnosis) applications. We will offer a description of how, at the current state of the art, similar nanomedicine platforms are realized.

AB - Nanoparticles (NPnanoparticle (NP)s) are extremely small particulates with an average size that ranges from a micron or less to a few nanometers. The large majority of NPs necessitate nanotechnology methods for their production. The size of NPs may vary over a significant range, which underlies their scientific potential in that NPs may help cross the bridge between bulk materials and molecular structures. More importantly, NPs are (nano)tech products and thus, in contrast to natural systems, they can be designed and engineered. On directly interacting with cells, including the structures of cells, their machinery and their waste products, NPs represent an unprecedented tool for addressing specific biological problems. In this chapter, we will briefly review some recent advances in nanoparticle research for biomedical applications, ranging from mesoporous silicon particles to gold and silver nanoparticles and polymeric nanocarriers for therapeutic, diagnosis, or theranostic (therapeutics + diagnosis) applications. We will offer a description of how, at the current state of the art, similar nanomedicine platforms are realized.

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BT - Springer Handbook of Nanotechnology

PB - Springer Berlin Heidelberg

ER -

Nano-particles for biomedical applications

Abstract

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