Abstract
We provide a high-level survey of multiscale molecular visualization techniques, with a focus on application-domain questions, challenges, and tasks. We provide a general introduction to molecular visualization basics and describe a number of domain-specific tasks that drive this work. These tasks, in turn, serve as the general structure of the following survey. First, we discuss methods that support the visual analysis of molecular dynamics simulations. We discuss, in particular, visual abstraction and temporal aggregation. In the second part, we survey multiscale approaches that support the design, analysis, and manipulation of DNA nanostructures and related concepts for abstraction, scale transition, scale-dependent modeling, and navigation of the resulting abstraction spaces. In the third part of the survey, we showcase approaches that support interactive exploration within large structural biology assemblies up to the size of bacterial cells. We describe fundamental rendering techniques as well as approaches for element instantiation, visibility management, visual guidance, camera control, and support of depth perception. We close the survey with a brief listing of important tools that implement many of the discussed approaches and a conclusion that provides some research challenges in the field.
Original language | English (US) |
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Pages (from-to) | 1049-1070 |
Number of pages | 22 |
Journal | Journal of molecular biology |
Volume | 431 |
Issue number | 6 |
DOIs | |
State | Published - Mar 15 2019 |
Bibliographical note
Publisher Copyright:© 2018
Keywords
- DNA nanotechnology
- modelitics
- molecular dynamics
- molecular visualization
- visual abstraction
ASJC Scopus subject areas
- Biophysics
- Structural Biology
- Molecular Biology