Moving with purpose and direction: transcription factor movement and cell fate determination revisited

Shyam Gundu; Naheed Tabassum; Ikram Blilou

doi:10.1016/j.pbi.2020.08.003

Moving with purpose and direction: transcription factor movement and cell fate determination revisited

Shyam Gundu, Naheed Tabassum, Ikram Blilou

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Cell diversity in a multicellular organism relies on cell–cell communication where cells must receive positional information as input signals to adopt their proper cell fate in the right place and at the right time. This process is achieved through triggering signaling cascades that drive cellular changes during development. In plants, signaling through mobile transcription factors (TF) plays a central role in development. Rather than acting cell-autonomously and exclusive to their expression domains, many TFs move between cells and deploy regulatory networks and cell type-specific effectors to achieve their biological functions. Here, we highlight a few examples of mobile TFs central to cell fate specification in Arabidopsis.

Original language	English (US)
Pages (from-to)	124-132
Number of pages	9
Journal	Current Opinion in Plant Biology
Volume	57
DOIs	https://doi.org/10.1016/j.pbi.2020.08.003
State	Published - Sep 28 2020

Bibliographical note

KAUST Repository Item: Exported on 2020-10-05
Acknowledged KAUST grant number(s): BAS/1/1081-01-01
Acknowledgements: This study was supported by King Abdulah University of Science and Technology (KAUST) baseline funding BAS/1/1081-01-01 given to Ikram Blilou.

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10.1016/j.pbi.2020.08.003

https://repository.kaust.edu.sa/bitstream/10754/665419/1/moving%20with%20purpose.pdf

Cite this

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title = "Moving with purpose and direction: transcription factor movement and cell fate determination revisited",

abstract = "Cell diversity in a multicellular organism relies on cell–cell communication where cells must receive positional information as input signals to adopt their proper cell fate in the right place and at the right time. This process is achieved through triggering signaling cascades that drive cellular changes during development. In plants, signaling through mobile transcription factors (TF) plays a central role in development. Rather than acting cell-autonomously and exclusive to their expression domains, many TFs move between cells and deploy regulatory networks and cell type-specific effectors to achieve their biological functions. Here, we highlight a few examples of mobile TFs central to cell fate specification in Arabidopsis.",

author = "Shyam Gundu and Naheed Tabassum and Ikram Blilou",

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doi = "10.1016/j.pbi.2020.08.003",

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AU - Tabassum, Naheed

AU - Blilou, Ikram

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Moving with purpose and direction: transcription factor movement and cell fate determination revisited

Abstract

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