Mini-review: Marine natural products and their synthetic analogs as antifouling compounds: 2009–2014

Pei-Yuan Qian; Zhongrui Li; Ying Xu; Yongxin Li; Nobuhiro Fusetani

doi:10.1080/08927014.2014.997226

Mini-review: Marine natural products and their synthetic analogs as antifouling compounds: 2009–2014

Pei-Yuan Qian, Zhongrui Li, Ying Xu, Yongxin Li, Nobuhiro Fusetani

Research output: Contribution to journal › Article › peer-review

174 Scopus citations

Abstract

This review covers 214 marine natural compounds and 23 of their synthetic analogs, which were discovered and/or synthesized from mid-2009 to August 2014. The antifouling (AF) compounds reported have medium to high bioactivity (with a threshold of EC50 < 15.0 mg ml−1). Among these compounds, 82 natural compounds were identified as new structures. All the compounds are marine-derived, demonstrating that marine organisms are prolific and promising sources of natural products that may be developed as environmentally friendly antifoulants. However, this mini-review excludes more than 200 compounds that were also reported as AF compounds but with rather weak bioactivity during the same period. Also excluded are terrestrial-derived AF compounds reported during the last five years. A brief discussion on current challenges in AF compound research is also provided to reflect the authors’ own views in terms of future research directions.

Original language	English (US)
Pages (from-to)	101-122
Number of pages	22
Journal	Biofouling
Volume	31
Issue number	1
DOIs	https://doi.org/10.1080/08927014.2014.997226
State	Published - Jan 26 2015
Externally published	Yes

Bibliographical note

KAUST Repository Item: Exported on 2021-03-31
Acknowledged KAUST grant number(s): SA-C0040/UK-C0016
Acknowledgements: This work was supported by a grant [DY125-15-T-02] from the China Ocean Mineral Resources Research and Development Association, a grant [SIDSSE-201206] from the Sanya Institute of Deep Sea Science and Engineering, a GRC grant [GRF661611] from Hong Kong Special Administrative Region, and award [SA-C0040/UK-C0016] from King Abdullah University of Science and Technology.
This publication acknowledges KAUST support, but has no KAUST affiliated authors.

ASJC Scopus subject areas

Applied Microbiology and Biotechnology
Water Science and Technology
Aquatic Science

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/08927014.2014.997226

Cite this

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abstract = "This review covers 214 marine natural compounds and 23 of their synthetic analogs, which were discovered and/or synthesized from mid-2009 to August 2014. The antifouling (AF) compounds reported have medium to high bioactivity (with a threshold of EC50 < 15.0 mg ml−1). Among these compounds, 82 natural compounds were identified as new structures. All the compounds are marine-derived, demonstrating that marine organisms are prolific and promising sources of natural products that may be developed as environmentally friendly antifoulants. However, this mini-review excludes more than 200 compounds that were also reported as AF compounds but with rather weak bioactivity during the same period. Also excluded are terrestrial-derived AF compounds reported during the last five years. A brief discussion on current challenges in AF compound research is also provided to reflect the authors{\textquoteright} own views in terms of future research directions.",

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note = "KAUST Repository Item: Exported on 2021-03-31 Acknowledged KAUST grant number(s): SA-C0040/UK-C0016 Acknowledgements: This work was supported by a grant [DY125-15-T-02] from the China Ocean Mineral Resources Research and Development Association, a grant [SIDSSE-201206] from the Sanya Institute of Deep Sea Science and Engineering, a GRC grant [GRF661611] from Hong Kong Special Administrative Region, and award [SA-C0040/UK-C0016] from King Abdullah University of Science and Technology. This publication acknowledges KAUST support, but has no KAUST affiliated authors.",

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Mini-review: Marine natural products and their synthetic analogs as antifouling compounds: 2009–2014

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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