Mapping three-dimensional temperature in microfluidic chip.

Jinbo Wu; Tsz Yan Kwok; Xiaolin Li; Wenbin Cao; Yu Wang; Junying Huang; Yaying Hong; Dongen Zhang; Weijia Wen

doi:10.1038/srep03321

Mapping three-dimensional temperature in microfluidic chip.

Jinbo Wu, Tsz Yan Kwok, Xiaolin Li, Wenbin Cao, Yu Wang, Junying Huang, Yaying Hong, Dongen Zhang, Weijia Wen

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Three-dimensional (3D) temperature mapping method with high spatial resolution and acquisition rate is of vital importance in evaluating thermal processes in micro-environment. We have synthesized a new temperature-sensitive functional material (Rhodamine B functionalized Polydimethylsiloxane). By performing optical sectioning of this material, we established an advanced method for visualizing the micro-scale 3D thermal distribution inside microfluidic chip with down to 10 ms temporal resolution and 2 ~ 6 °C temperature resolution depending the capture parameters. This method is successfully applied to monitor the local temperature variation throughout micro-droplet heat transfer process and further reveal exothermic nanoliter droplet reactions to be unique and milder than bench-top experiment.

Original language	English (US)
Journal	Scientific Reports
Volume	3
Issue number	1
DOIs	https://doi.org/10.1038/srep03321
State	Published - Nov 25 2013
Externally published	Yes

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledged KAUST grant number(s): SA-C0040/UK-C0016
Acknowledgements: The authors acknowledge the financial support provided by the Hong Kong Research Grants Council Grant No. HKUST 604710 and HKUST 605411. This publication is based on work partially supported by Award No. SA-C0040/UK-C0016 made by King Abdullah University of Science and Technology (KAUST).
This publication acknowledges KAUST support, but has no KAUST affiliated authors.

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10.1038/srep03321

https://repository.kaust.edu.sa/bitstream/10754/596800/1/PMC3839638.pdf

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title = "Mapping three-dimensional temperature in microfluidic chip.",

abstract = "Three-dimensional (3D) temperature mapping method with high spatial resolution and acquisition rate is of vital importance in evaluating thermal processes in micro-environment. We have synthesized a new temperature-sensitive functional material (Rhodamine B functionalized Polydimethylsiloxane). By performing optical sectioning of this material, we established an advanced method for visualizing the micro-scale 3D thermal distribution inside microfluidic chip with down to 10 ms temporal resolution and 2 ~ 6 °C temperature resolution depending the capture parameters. This method is successfully applied to monitor the local temperature variation throughout micro-droplet heat transfer process and further reveal exothermic nanoliter droplet reactions to be unique and milder than bench-top experiment.",

author = "Jinbo Wu and Kwok, {Tsz Yan} and Xiaolin Li and Wenbin Cao and Yu Wang and Junying Huang and Yaying Hong and Dongen Zhang and Weijia Wen",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledged KAUST grant number(s): SA-C0040/UK-C0016 Acknowledgements: The authors acknowledge the financial support provided by the Hong Kong Research Grants Council Grant No. HKUST 604710 and HKUST 605411. This publication is based on work partially supported by Award No. SA-C0040/UK-C0016 made by King Abdullah University of Science and Technology (KAUST). This publication acknowledges KAUST support, but has no KAUST affiliated authors.",

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doi = "10.1038/srep03321",

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AU - Wu, Jinbo

AU - Kwok, Tsz Yan

AU - Li, Xiaolin

AU - Cao, Wenbin

AU - Wang, Yu

AU - Huang, Junying

AU - Hong, Yaying

AU - Zhang, Dongen

AU - Wen, Weijia

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledged KAUST grant number(s): SA-C0040/UK-C0016 Acknowledgements: The authors acknowledge the financial support provided by the Hong Kong Research Grants Council Grant No. HKUST 604710 and HKUST 605411. This publication is based on work partially supported by Award No. SA-C0040/UK-C0016 made by King Abdullah University of Science and Technology (KAUST). This publication acknowledges KAUST support, but has no KAUST affiliated authors.

PY - 2013/11/25

Y1 - 2013/11/25

N2 - Three-dimensional (3D) temperature mapping method with high spatial resolution and acquisition rate is of vital importance in evaluating thermal processes in micro-environment. We have synthesized a new temperature-sensitive functional material (Rhodamine B functionalized Polydimethylsiloxane). By performing optical sectioning of this material, we established an advanced method for visualizing the micro-scale 3D thermal distribution inside microfluidic chip with down to 10 ms temporal resolution and 2 ~ 6 °C temperature resolution depending the capture parameters. This method is successfully applied to monitor the local temperature variation throughout micro-droplet heat transfer process and further reveal exothermic nanoliter droplet reactions to be unique and milder than bench-top experiment.

AB - Three-dimensional (3D) temperature mapping method with high spatial resolution and acquisition rate is of vital importance in evaluating thermal processes in micro-environment. We have synthesized a new temperature-sensitive functional material (Rhodamine B functionalized Polydimethylsiloxane). By performing optical sectioning of this material, we established an advanced method for visualizing the micro-scale 3D thermal distribution inside microfluidic chip with down to 10 ms temporal resolution and 2 ~ 6 °C temperature resolution depending the capture parameters. This method is successfully applied to monitor the local temperature variation throughout micro-droplet heat transfer process and further reveal exothermic nanoliter droplet reactions to be unique and milder than bench-top experiment.

UR - http://hdl.handle.net/10754/596800

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JO - Scientific Reports

JF - Scientific Reports

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Mapping three-dimensional temperature in microfluidic chip.

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