Mapping three-dimensional temperature in microfluidic chip.

Jinbo Wu, Tsz Yan Kwok, Xiaolin Li, Wenbin Cao, Yu Wang, Junying Huang, Yaying Hong, Dongen Zhang, Weijia Wen

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Three-dimensional (3D) temperature mapping method with high spatial resolution and acquisition rate is of vital importance in evaluating thermal processes in micro-environment. We have synthesized a new temperature-sensitive functional material (Rhodamine B functionalized Polydimethylsiloxane). By performing optical sectioning of this material, we established an advanced method for visualizing the micro-scale 3D thermal distribution inside microfluidic chip with down to 10 ms temporal resolution and 2 ~ 6 °C temperature resolution depending the capture parameters. This method is successfully applied to monitor the local temperature variation throughout micro-droplet heat transfer process and further reveal exothermic nanoliter droplet reactions to be unique and milder than bench-top experiment.
Original languageEnglish (US)
JournalScientific Reports
Issue number1
StatePublished - Nov 25 2013
Externally publishedYes

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledged KAUST grant number(s): SA-C0040/UK-C0016
Acknowledgements: The authors acknowledge the financial support provided by the Hong Kong Research Grants Council Grant No. HKUST 604710 and HKUST 605411. This publication is based on work partially supported by Award No. SA-C0040/UK-C0016 made by King Abdullah University of Science and Technology (KAUST).
This publication acknowledges KAUST support, but has no KAUST affiliated authors.


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