Magnetic/silica nanocomposites as dual-mode contrast agents for combined magnetic resonance imaging and ultrasonography

Maria Ada Malvindi; Antonio Greco; Francesco Conversano; Albert Figuerola; Maurizio Corti; Marco Bonora; Alessandro Lascialfari; Houshang Amiri Doumari; Marco Moscardini; Roberto Cingolani; Giuseppe Gigli; Sergio Casciaro; Teresa Pellegrino; Andrea Ragusa

doi:10.1002/adfm.201100031

Magnetic/silica nanocomposites as dual-mode contrast agents for combined magnetic resonance imaging and ultrasonography

Maria Ada Malvindi, Antonio Greco, Francesco Conversano, Albert Figuerola, Maurizio Corti, Marco Bonora, Alessandro Lascialfari, Houshang Amiri Doumari, Marco Moscardini, Roberto Cingolani, Giuseppe Gigli, Sergio Casciaro, Teresa Pellegrino, Andrea Ragusa^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

86 Scopus citations

Abstract

A simple and efficient method for synthesizing a range of hybrid nanocomposites based on a core of silica nanospheres (160, 330, and 660 nm in diameter) covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt-iron oxide nanocrystals, is presented. The magnetic and ultrasound characterization of the resulting nanocomposites shows that they have great potential as contrast agents for dual-mode imaging purposes, combining magnetic resonance imaging (MRI) and ultrasonography (US). The synthesis of a range of hybrid nanocomposites based on a core of silica covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt-iron oxide nanocrystals, is presented. The nanocomposites show potential as contrast agents for dual-mode imaging purposes, combining magnetic resonance imaging and ultrasonography.

Original language	English (US)
Pages (from-to)	2548-2555
Number of pages	8
Journal	Advanced Functional Materials
Volume	21
Issue number	13
DOIs	https://doi.org/10.1002/adfm.201100031
State	Published - Jul 8 2011
Externally published	Yes

Keywords

MRI
biomedical applications
composite materials
core-shell nanoparticles
magnetic nanoparticles
silica
ultrasonography

ASJC Scopus subject areas

General Chemistry
General Materials Science
Condensed Matter Physics

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Malvindi, M. A., Greco, A., Conversano, F., Figuerola, A., Corti, M., Bonora, M., Lascialfari, A., Doumari, H. A., Moscardini, M., Cingolani, R., Gigli, G., Casciaro, S., Pellegrino, T., & Ragusa, A. (2011). Magnetic/silica nanocomposites as dual-mode contrast agents for combined magnetic resonance imaging and ultrasonography. Advanced Functional Materials, 21(13), 2548-2555. https://doi.org/10.1002/adfm.201100031

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title = "Magnetic/silica nanocomposites as dual-mode contrast agents for combined magnetic resonance imaging and ultrasonography",

abstract = "A simple and efficient method for synthesizing a range of hybrid nanocomposites based on a core of silica nanospheres (160, 330, and 660 nm in diameter) covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt-iron oxide nanocrystals, is presented. The magnetic and ultrasound characterization of the resulting nanocomposites shows that they have great potential as contrast agents for dual-mode imaging purposes, combining magnetic resonance imaging (MRI) and ultrasonography (US). The synthesis of a range of hybrid nanocomposites based on a core of silica covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt-iron oxide nanocrystals, is presented. The nanocomposites show potential as contrast agents for dual-mode imaging purposes, combining magnetic resonance imaging and ultrasonography.",

keywords = "MRI, biomedical applications, composite materials, core-shell nanoparticles, magnetic nanoparticles, silica, ultrasonography",

author = "Malvindi, {Maria Ada} and Antonio Greco and Francesco Conversano and Albert Figuerola and Maurizio Corti and Marco Bonora and Alessandro Lascialfari and Doumari, {Houshang Amiri} and Marco Moscardini and Roberto Cingolani and Giuseppe Gigli and Sergio Casciaro and Teresa Pellegrino and Andrea Ragusa",

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Malvindi, MA, Greco, A, Conversano, F, Figuerola, A, Corti, M, Bonora, M, Lascialfari, A, Doumari, HA, Moscardini, M, Cingolani, R, Gigli, G, Casciaro, S, Pellegrino, T & Ragusa, A 2011, 'Magnetic/silica nanocomposites as dual-mode contrast agents for combined magnetic resonance imaging and ultrasonography', Advanced Functional Materials, vol. 21, no. 13, pp. 2548-2555. https://doi.org/10.1002/adfm.201100031

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T1 - Magnetic/silica nanocomposites as dual-mode contrast agents for combined magnetic resonance imaging and ultrasonography

AU - Malvindi, Maria Ada

AU - Greco, Antonio

AU - Conversano, Francesco

AU - Figuerola, Albert

AU - Corti, Maurizio

AU - Bonora, Marco

AU - Lascialfari, Alessandro

AU - Doumari, Houshang Amiri

AU - Moscardini, Marco

AU - Cingolani, Roberto

AU - Gigli, Giuseppe

AU - Casciaro, Sergio

AU - Pellegrino, Teresa

AU - Ragusa, Andrea

PY - 2011/7/8

Y1 - 2011/7/8

N2 - A simple and efficient method for synthesizing a range of hybrid nanocomposites based on a core of silica nanospheres (160, 330, and 660 nm in diameter) covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt-iron oxide nanocrystals, is presented. The magnetic and ultrasound characterization of the resulting nanocomposites shows that they have great potential as contrast agents for dual-mode imaging purposes, combining magnetic resonance imaging (MRI) and ultrasonography (US). The synthesis of a range of hybrid nanocomposites based on a core of silica covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt-iron oxide nanocrystals, is presented. The nanocomposites show potential as contrast agents for dual-mode imaging purposes, combining magnetic resonance imaging and ultrasonography.

AB - A simple and efficient method for synthesizing a range of hybrid nanocomposites based on a core of silica nanospheres (160, 330, and 660 nm in diameter) covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt-iron oxide nanocrystals, is presented. The magnetic and ultrasound characterization of the resulting nanocomposites shows that they have great potential as contrast agents for dual-mode imaging purposes, combining magnetic resonance imaging (MRI) and ultrasonography (US). The synthesis of a range of hybrid nanocomposites based on a core of silica covered by an outer shell of superparamagnetic nanoparticles, either iron oxide or heterodimeric FePt-iron oxide nanocrystals, is presented. The nanocomposites show potential as contrast agents for dual-mode imaging purposes, combining magnetic resonance imaging and ultrasonography.

KW - MRI

KW - biomedical applications

KW - composite materials

KW - core-shell nanoparticles

KW - magnetic nanoparticles

KW - silica

KW - ultrasonography

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DO - 10.1002/adfm.201100031

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VL - 21

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JO - Advanced Functional Materials

JF - Advanced Functional Materials

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ER -

Magnetic/silica nanocomposites as dual-mode contrast agents for combined magnetic resonance imaging and ultrasonography

Abstract

Keywords

ASJC Scopus subject areas

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