Owing to their high surface area and porosity, metal-organic frameworks (MOFs) have been gradually employed for a myriad of applications ranging from sensing, pollutant adsorption, and drug delivery to environmental remediation and catalysis. Magnetic nanoparticles-metal-organic frameworks (MMOFs) hybrid materials can facilitate facile removal of MOFs from solutions. In this report, we report the synthesis of Fe3O4@UiO-66 by encapsulation and simulated the drug loading and release by studying the adsorption and release of AO7. Thus, we loaded these MMOFs with AO7 and found that they were able to trigger and control its release by simply applying an external magnetic field. The magnetic field heats the magnets in the MOF, which causes the load to burst from the framework.
Bibliographical noteFunding Information:
capacity (140 mg/g) comparable to the conventional UiO-66 (140 mg/g) and the release rate of the dye under the action of methanol are also considerable. By comparing the properties and structure of AO7 with similar drugs, we think some drugs such as Aspirin and Iressa can also be adsorbed by down, whichensuresthat the drugis better absorbed by the body.Some promising applicationsin Fe3O4@UiO-66. Because of the effect of pH on drug release, the rate of release is somewhat slowed industrialsustainability,medicalprocesses,andenvironment-relatedareasarealsodiscussed. down, which ensures that the drug is better absorbed by the body. Some promising applications in indusSturpiapllesmusetnatainryaMbialitteyri,amls:eTdhiecafolllporwoicnegsasreesa,vaanildabelenovnilrionenamtwenwtw-r.emladtpeid.coamr/exaxsx/as1r,eVaildseoo:dFies3cOu4@ssUeiOd-.66 dispersioninthepresenceofamagnetfield. Supplementary Materials: The following are available online at http://www.mdpi.com/2073-4352/8/6/250/s1, AuthorContributions:Themanuscriptwaswrittenthroughcontributionsofallauthors.Allauthorshavegiven Video: Fe3O4@UiO-66 dispersion in the presence of a magnet field. approvaltothefinalversionofthemanuscript. Author Contributions: The manuscript was written through contributions of all authors. All authors have given approvalAckntoowtheledfinalgemeversionnt: Thisofsttheudymanuscript.has been supported by the National High Technology Research and Development Program (863 program) of China No. 2012AA06A111; Hubei Provincial Natural Science FoundationofChinaNo.2014CFB552;HubeiCollaborativeInnovationCenterforAdvancedOrganicChemical Program (863 program) of China No. 2012AA06A111; Hubei Provincial Natural Science Foundation of China MaterialsofChinaNo.000-01647909. No. 2014CFB552; Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials of China No. 00C0o-n0f1l6ic4t7s9o0f9I.nterest:Theauthorsdeclarenoconflictofinterest.
This study has been supported by the National High Technology Research and Development Program (863 program) of China No. 2012AA06A111; Hubei Provincial Natural Science Foundation of China No. 2014CFB552; Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials of China No. 000-01647909.
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- Magnetic MOFs
- Targeted delivery
- Triggered release
ASJC Scopus subject areas
- Chemical Engineering(all)
- Materials Science(all)
- Condensed Matter Physics
- Inorganic Chemistry