Magnetic MOF for AO7 removal and targeted delivery

Xue Qing Zhan; Xiao Yan Yu; Fang Chang Tsai; Ning Ma; Huan Li Liu; Yu Han; Lei Xie; Tao Jiang; Dean Shi; Yan Xiong

doi:10.3390/cryst8060250

Magnetic MOF for AO7 removal and targeted delivery

Xue Qing Zhan, Xiao Yan Yu, Fang Chang Tsai^*, Ning Ma, Huan Li Liu, Yu Han, Lei Xie, Tao Jiang, Dean Shi, Yan Xiong

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Owing to their high surface area and porosity, metal-organic frameworks (MOFs) have been gradually employed for a myriad of applications ranging from sensing, pollutant adsorption, and drug delivery to environmental remediation and catalysis. Magnetic nanoparticles-metal-organic frameworks (MMOFs) hybrid materials can facilitate facile removal of MOFs from solutions. In this report, we report the synthesis of Fe₃O₄@UiO-66 by encapsulation and simulated the drug loading and release by studying the adsorption and release of AO7. Thus, we loaded these MMOFs with AO7 and found that they were able to trigger and control its release by simply applying an external magnetic field. The magnetic field heats the magnets in the MOF, which causes the load to burst from the framework.

Original language	English (US)
Article number	250
Journal	Crystals
Volume	8
Issue number	6
DOIs	https://doi.org/10.3390/cryst8060250
State	Published - Jun 15 2018

Bibliographical note

Publisher Copyright:
© 2018 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

AO7
Magnetic MOFs
Targeted delivery
Triggered release

ASJC Scopus subject areas

General Chemical Engineering
General Materials Science
Condensed Matter Physics
Inorganic Chemistry

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10.3390/cryst8060250

Cite this

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title = "Magnetic MOF for AO7 removal and targeted delivery",

abstract = "Owing to their high surface area and porosity, metal-organic frameworks (MOFs) have been gradually employed for a myriad of applications ranging from sensing, pollutant adsorption, and drug delivery to environmental remediation and catalysis. Magnetic nanoparticles-metal-organic frameworks (MMOFs) hybrid materials can facilitate facile removal of MOFs from solutions. In this report, we report the synthesis of Fe3O4@UiO-66 by encapsulation and simulated the drug loading and release by studying the adsorption and release of AO7. Thus, we loaded these MMOFs with AO7 and found that they were able to trigger and control its release by simply applying an external magnetic field. The magnetic field heats the magnets in the MOF, which causes the load to burst from the framework.",

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AU - Zhan, Xue Qing

AU - Yu, Xiao Yan

AU - Tsai, Fang Chang

AU - Ma, Ning

AU - Liu, Huan Li

AU - Han, Yu

AU - Xie, Lei

AU - Jiang, Tao

AU - Shi, Dean

AU - Xiong, Yan

PY - 2018/6/15

Y1 - 2018/6/15

N2 - Owing to their high surface area and porosity, metal-organic frameworks (MOFs) have been gradually employed for a myriad of applications ranging from sensing, pollutant adsorption, and drug delivery to environmental remediation and catalysis. Magnetic nanoparticles-metal-organic frameworks (MMOFs) hybrid materials can facilitate facile removal of MOFs from solutions. In this report, we report the synthesis of Fe3O4@UiO-66 by encapsulation and simulated the drug loading and release by studying the adsorption and release of AO7. Thus, we loaded these MMOFs with AO7 and found that they were able to trigger and control its release by simply applying an external magnetic field. The magnetic field heats the magnets in the MOF, which causes the load to burst from the framework.

AB - Owing to their high surface area and porosity, metal-organic frameworks (MOFs) have been gradually employed for a myriad of applications ranging from sensing, pollutant adsorption, and drug delivery to environmental remediation and catalysis. Magnetic nanoparticles-metal-organic frameworks (MMOFs) hybrid materials can facilitate facile removal of MOFs from solutions. In this report, we report the synthesis of Fe3O4@UiO-66 by encapsulation and simulated the drug loading and release by studying the adsorption and release of AO7. Thus, we loaded these MMOFs with AO7 and found that they were able to trigger and control its release by simply applying an external magnetic field. The magnetic field heats the magnets in the MOF, which causes the load to burst from the framework.

KW - AO7

KW - Magnetic MOFs

KW - Targeted delivery

KW - Triggered release

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Magnetic MOF for AO7 removal and targeted delivery

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

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