Interfacing glycosylated carbon-nanotube-network devices with living cells to detect dynamic secretion of biomolecules

Herry Gunadi Sudibya, Jimei Ma, Xiaochen Dong, Simon Ng, Lain Jong Li, Xue Wei Liu, Peng Chen

Research output: Contribution to journalArticlepeer-review

152 Scopus citations

Abstract

A sense of cell-being: Single-walled carbon nanotubes (SWNTs) are functionalized with bioactive monosaccharides to enable their use as biosensors. The glycosylated nanotube network is biocompatible and can interface with living cells (see scheme) to electronically detect biomolecular release with high temporal resolution and high sensitivity.

Original languageEnglish (US)
Pages (from-to)2723-2726
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number15
DOIs
StatePublished - Mar 30 2009
Externally publishedYes

Keywords

  • Bionanotechnology
  • Biosensors
  • Carbohydrates
  • Carbon nanotubes

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

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