In vivo local determination of tissue optical properties

Frederic Bevilacqua; D. Piguet; P. Marquet; J. D. Gross; B. J. Tromberg; C. Depeursinge

doi:10.1117/12.301063

In vivo local determination of tissue optical properties

Frederic Bevilacqua^*, D. Piguet, P. Marquet, J. D. Gross, B. J. Tromberg, C. Depeursinge

^*Corresponding author for this work

Research output: Contribution to journal › Conference article › peer-review

13 Scopus citations

Abstract

Local and superficial optical characterization of biological tissues can be achieved by measuring the spatially resolved diffuse reflectance at small source-detector separations. The sensitivity of the signal to the phase function, absorption and scattering coefficients were studied using Monte Carlo simulations. Measurements of spatially resolved reflectance were performed in vivo on human brain with source-detector separations from 0.3 to 1.5 mm. Distinct optical properties were found between normal cortex, astrocytoma of optic nerve and normal optic nerve.

Original language	English (US)
Pages (from-to)	262-268
Number of pages	7
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	3194
DOIs	https://doi.org/10.1117/12.301063
State	Published - 1997
Externally published	Yes
Event	Proceedings of Photon Propagation in Tissues III - San Remo, Italy Duration: Sep 6 1997 → Sep 8 1997

Keywords

Absorption coefficient
Optical biopsy
Optical properties
Scattering coefficient
Tissue optics
Turbid media

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

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10.1117/12.301063

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@article{f3ebcc11ec244146bb0053a989fb6f8c,

title = "In vivo local determination of tissue optical properties",

abstract = "Local and superficial optical characterization of biological tissues can be achieved by measuring the spatially resolved diffuse reflectance at small source-detector separations. The sensitivity of the signal to the phase function, absorption and scattering coefficients were studied using Monte Carlo simulations. Measurements of spatially resolved reflectance were performed in vivo on human brain with source-detector separations from 0.3 to 1.5 mm. Distinct optical properties were found between normal cortex, astrocytoma of optic nerve and normal optic nerve.",

keywords = "Absorption coefficient, Optical biopsy, Optical properties, Scattering coefficient, Tissue optics, Turbid media",

author = "Frederic Bevilacqua and D. Piguet and P. Marquet and Gross, {J. D.} and Tromberg, {B. J.} and C. Depeursinge",

year = "1997",

doi = "10.1117/12.301063",

language = "English (US)",

volume = "3194",

pages = "262--268",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

issn = "0277-786X",

publisher = "SPIE",

note = "Proceedings of Photon Propagation in Tissues III ; Conference date: 06-09-1997 Through 08-09-1997",

}

TY - JOUR

T1 - In vivo local determination of tissue optical properties

AU - Bevilacqua, Frederic

AU - Piguet, D.

AU - Marquet, P.

AU - Gross, J. D.

AU - Tromberg, B. J.

AU - Depeursinge, C.

PY - 1997

Y1 - 1997

N2 - Local and superficial optical characterization of biological tissues can be achieved by measuring the spatially resolved diffuse reflectance at small source-detector separations. The sensitivity of the signal to the phase function, absorption and scattering coefficients were studied using Monte Carlo simulations. Measurements of spatially resolved reflectance were performed in vivo on human brain with source-detector separations from 0.3 to 1.5 mm. Distinct optical properties were found between normal cortex, astrocytoma of optic nerve and normal optic nerve.

AB - Local and superficial optical characterization of biological tissues can be achieved by measuring the spatially resolved diffuse reflectance at small source-detector separations. The sensitivity of the signal to the phase function, absorption and scattering coefficients were studied using Monte Carlo simulations. Measurements of spatially resolved reflectance were performed in vivo on human brain with source-detector separations from 0.3 to 1.5 mm. Distinct optical properties were found between normal cortex, astrocytoma of optic nerve and normal optic nerve.

KW - Absorption coefficient

KW - Optical biopsy

KW - Optical properties

KW - Scattering coefficient

KW - Tissue optics

KW - Turbid media

UR - http://www.scopus.com/inward/record.url?scp=0031289592&partnerID=8YFLogxK

U2 - 10.1117/12.301063

DO - 10.1117/12.301063

M3 - Conference article

AN - SCOPUS:0031289592

SN - 0277-786X

VL - 3194

SP - 262

EP - 268

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Proceedings of Photon Propagation in Tissues III

Y2 - 6 September 1997 through 8 September 1997

ER -

In vivo local determination of tissue optical properties

Abstract

Keywords

ASJC Scopus subject areas

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