In situ nasal gel drug delivery: A novel approach for brain targeting through the mucosal membrane

Prabhjot Kaur, Tarun Garg, Goutam Rath, Amit K. Goyal

Research output: Contribution to journalArticlepeer-review

81 Scopus citations

Abstract

Recently, sustained and controlled drug delivery has become the demand, and research has been undertaken in achieving much better drug product effectiveness, reliability and safety. The in situ polymeric system has gained much attention, to develop a controlled release system. It has been used as a vehicle for local and systemic drug delivery. Nowadays, it has created much interest, because of its characteristics of high vascularization, high permeability, rapid onset of action, low enzymatic degradation, and avoidance of hepatic first pass metabolism. The main aim of this review is to provide knowledge of different mechanisms of nasal absorption and approaches for nasal drug delivery.
Original languageEnglish (US)
Pages (from-to)1167-1176
Number of pages10
JournalArtificial Cells, Nanomedicine and Biotechnology
Volume44
Issue number4
DOIs
StatePublished - May 18 2016
Externally publishedYes

Bibliographical note

Generated from Scopus record by KAUST IRTS on 2023-10-12

ASJC Scopus subject areas

  • Biotechnology
  • Biomedical Engineering
  • Pharmaceutical Science
  • Medicine (miscellaneous)

Fingerprint

Dive into the research topics of 'In situ nasal gel drug delivery: A novel approach for brain targeting through the mucosal membrane'. Together they form a unique fingerprint.

Cite this