Abstract
SUMMARY: MODalign is an interactive web-based tool aimed at helping protein structure modelers to inspect and manually modify the alignment between the sequences of a target protein and of its template(s). It interactively computes, displays and, upon modification of the target-template alignment, updates the multiple sequence alignments of the two protein families, their conservation score, secondary structure and solvent accessibility values, and local quality scores of the implied three-dimensional model(s). Although it has been designed to simplify the target-template alignment step in modeling, it is suitable for all cases where a sequence alignment needs to be inspected in the context of other biological information. AVAILABILITY AND IMPLEMENTATION: Freely available on the web at http://modorama.biocomputing.it/modalign. Website implemented in HTML and JavaScript with all major browsers supported. CONTACT: [email protected].
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1038-1039 |
| Number of pages | 2 |
| Journal | Bioinformatics |
| Volume | 28 |
| Issue number | 7 |
| DOIs | |
| State | Published - Feb 4 2012 |
| Externally published | Yes |
Bibliographical note
KAUST Repository Item: Exported on 2020-10-01Acknowledged KAUST grant number(s): KUK-I1-012-43
Acknowledgements: KAUST Award No. KUK-I1-012-43 made by King Abdullah University of Science and Technology (KAUST), Fondazione Roma, the Italian Ministry of Health, Contract No. onc_ord 25/07, FIRB PROTEOMICA, and European Molecular Biology Organization (EMBO) long-term fellowship to J.K.
This publication acknowledges KAUST support, but has no KAUST affiliated authors.