Important Flavonoids and Their Role as a Therapeutic Agent

Asad Ullah, Sidra Munir, Syed Lal Badshah, Noreen Khan, Lubna Ghani, Benjamin Gabriel Poulson, Abdul-Hamid M. Emwas, Mariusz Jaremko

Research output: Contribution to journalArticlepeer-review

549 Scopus citations

Abstract

Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuroprotective and cardio-protective effects. These biological activities depend upon the type of flavonoid, its (possible) mode of action, and its bioavailability. These cost-effective medicinal components have significant biological activities, and their effectiveness has been proved for a variety of diseases. The most recent work is focused on their isolation, synthesis of their analogs, and their effects on human health using a variety of techniques and animal models. Thousands of flavonoids have been successfully isolated, and this number increases steadily. We have therefore made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.
Original languageEnglish (US)
Pages (from-to)5243
JournalMolecules
Volume25
Issue number22
DOIs
StatePublished - Nov 11 2020

Bibliographical note

KAUST Repository Item: Exported on 2020-11-12
Acknowledgements: Mariusz Jaremko; Benjamin Gabriel Poulson and Abdul-Hamid Emwas would like to thanks King Abdullah University of Science and Technology for the financial support.

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