Identification of a novel gene coding for neoxanthin synthase from Solanum tuberosum

Salim Al-Babili, Philippe Hugueney, Michael Schledz, Ralf Welsch, Hanns Frohnmeyer, Oliver Laule, Peter Beyer*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

88 Scopus citations


The polymerase chain reaction analysis of potato plants, transformed with capsanthin capsorubin synthase ccs, revealed the presence of a highly related gene. The cloned cDNA showed at the protein level 89.6% identity to CCS. This suggested that the novel enzyme catalyzes a mechanistically similar reaction. Such a reaction is represented by neoxanthin synthase (NXS), forming the xanthophyll neoxanthin, a direct substrate for abscisic acid formation. The function of the novel enzyme could be proven by transient expression in plant protoplasts and high performance liquid chromatography analysis. The cloned NXS was imported in vitro into plastids, the compartment of carotenoid biosynthesis. (C) 2000 Federation of European Biochemical Societies.

Original languageEnglish (US)
Pages (from-to)168-172
Number of pages5
JournalFEBS Letters
Issue number2-3
StatePublished - Nov 24 2000


  • Abscisic acid
  • Capsanthin capsorubin synthase
  • Carotenoid
  • Neoxanthin synthase
  • Violaxanthin

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology


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