TY - JOUR
T1 - I2/Li2CO3-promoted cyanation of diarylalcohols through a dual activation process
AU - Hu, Liangzhen
AU - Hussain, Muhammad Ijaz
AU - Deng, Qingfu
AU - Liu, Qing
AU - Feng, Yangyang
AU - Zhang, Xiaohui
AU - Xiong, Yan
N1 - Generated from Scopus record by KAUST IRTS on 2023-10-22
PY - 2019/1/11
Y1 - 2019/1/11
N2 - One-step base promoted strategy for cyanation of α,α-diaryl alcohols has been developed under mild and transition metal-free conditions. This method provides a straightforward and facile way towards the synthesis of β,γ-unsaturated nitriles and α-phenylnitiriles from α-vinyl carbinols and α,α-diaryl methanols, respectively, up to 99% yield. Moreover, various azides and ethers could also be accessed from their respective nucleophiles under standard reaction conditions.
AB - One-step base promoted strategy for cyanation of α,α-diaryl alcohols has been developed under mild and transition metal-free conditions. This method provides a straightforward and facile way towards the synthesis of β,γ-unsaturated nitriles and α-phenylnitiriles from α-vinyl carbinols and α,α-diaryl methanols, respectively, up to 99% yield. Moreover, various azides and ethers could also be accessed from their respective nucleophiles under standard reaction conditions.
UR - https://linkinghub.elsevier.com/retrieve/pii/S0040402018314595
UR - http://www.scopus.com/inward/record.url?scp=85057727456&partnerID=8YFLogxK
U2 - 10.1016/j.tet.2018.11.069
DO - 10.1016/j.tet.2018.11.069
M3 - Article
SN - 0040-4020
VL - 75
SP - 308
EP - 314
JO - Tetrahedron
JF - Tetrahedron
IS - 2
ER -