Hydrotrifluoromethylthiolation of α-diazo esters – synthesis of α-SCF3 substituted esters

Quentin Lefebvre; Eleonora Fava; Pavlo Nikolaienko; Magnus Rueping

doi:10.1039/c4cc02060j

Hydrotrifluoromethylthiolation of α-diazo esters – synthesis of α-SCF₃ substituted esters

Quentin Lefebvre, Eleonora Fava, Pavlo Nikolaienko, Magnus Rueping^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

108 Scopus citations

Abstract

A practical protocol for hydrotrifluoromethylthiolation of diazo compounds has been developed. A range of diazo compounds in combination with a nucleophilic SCF₃ source provided access to valuable trifluoromethylthiolated compounds. Furthermore, a methodology for the first double trifluoromethylthiolation was developed.

Original language	English (US)
Pages (from-to)	6617-6619
Number of pages	3
Journal	CHEMICAL COMMUNICATIONS
Volume	50
Issue number	50
DOIs	https://doi.org/10.1039/c4cc02060j
State	Published - May 27 2014
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
General Chemistry
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Catalysis

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10.1039/c4cc02060j

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abstract = "A practical protocol for hydrotrifluoromethylthiolation of diazo compounds has been developed. A range of diazo compounds in combination with a nucleophilic SCF3 source provided access to valuable trifluoromethylthiolated compounds. Furthermore, a methodology for the first double trifluoromethylthiolation was developed.",

author = "Quentin Lefebvre and Eleonora Fava and Pavlo Nikolaienko and Magnus Rueping",

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AU - Lefebvre, Quentin

AU - Fava, Eleonora

AU - Nikolaienko, Pavlo

AU - Rueping, Magnus

PY - 2014/5/27

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AB - A practical protocol for hydrotrifluoromethylthiolation of diazo compounds has been developed. A range of diazo compounds in combination with a nucleophilic SCF3 source provided access to valuable trifluoromethylthiolated compounds. Furthermore, a methodology for the first double trifluoromethylthiolation was developed.

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Hydrotrifluoromethylthiolation of α-diazo esters – synthesis of α-SCF₃ substituted esters

Abstract

ASJC Scopus subject areas

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