Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer

Selma Amara; Ride Bu; Meshal Alawein; Nouf Alsharif; Mohammed Asadullah Khan; Yan Wen; Xixiang Zhang; Jurgen Kosel; Hossein Fariborzi

doi:10.1109/MeMeA.2018.8438652

Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer

Selma Amara, Ride Bu, Meshal Alawein, Nouf Alsharif, Mohammed Asadullah Khan, Yan Wen, Xixiang Zhang, Jurgen Kosel, Hossein Fariborzi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Scopus citations

Abstract

Flow cytometers are important instruments for biological and biomedical analyses. These instruments are large and expensive, and researchers are continuously striving to come up with smaller, cheaper, and more energy-efficient flow cytometers. In this work, we present a highly-sensitive magnetic tunnel junction (MTJ) based flow cytometer. An externally magnetized magnetic beads labeling cells were placed above an MTJ sensor that can measure the stray field surrounding the beads. It was found that each time labeled cells pass through the sensitive area of the sensor, a peak of signal was observed. The results demonstrate a novel MTJ based flow cytometer design approach for accurate detection of magnetically labeled cells.

Original language	English (US)
Title of host publication	MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Print)	9781538633915
DOIs	https://doi.org/10.1109/MeMeA.2018.8438652
State	Published - Aug 16 2018
Event	13th IEEE International Symposium on Medical Measurements and Applications, MeMeA 2018 - Rome, Italy Duration: Jun 11 2018 → Jun 13 2018

Publication series

Name	MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings

Conference

Conference	13th IEEE International Symposium on Medical Measurements and Applications, MeMeA 2018
Country/Territory	Italy
City	Rome
Period	06/11/18 → 06/13/18

Bibliographical note

Publisher Copyright:
© 2018 IEEE.

Keywords

Biosensor
PDMS microchannel
flow cytometer
magnetic bead
magnetic tunnel junction

ASJC Scopus subject areas

Instrumentation
Health Informatics
Biomedical Engineering

Access to Document

10.1109/MeMeA.2018.8438652

Cite this

Amara, S., Bu, R., Alawein, M., Alsharif, N., Khan, M. A., Wen, Y., Zhang, X., Kosel, J., & Fariborzi, H. (2018). Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer. In MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings Article 8438652 (MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MeMeA.2018.8438652

Amara, Selma ; Bu, Ride ; Alawein, Meshal et al. / Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer. MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings. Institute of Electrical and Electronics Engineers Inc., 2018. (MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings).

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title = "Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer",

abstract = "Flow cytometers are important instruments for biological and biomedical analyses. These instruments are large and expensive, and researchers are continuously striving to come up with smaller, cheaper, and more energy-efficient flow cytometers. In this work, we present a highly-sensitive magnetic tunnel junction (MTJ) based flow cytometer. An externally magnetized magnetic beads labeling cells were placed above an MTJ sensor that can measure the stray field surrounding the beads. It was found that each time labeled cells pass through the sensitive area of the sensor, a peak of signal was observed. The results demonstrate a novel MTJ based flow cytometer design approach for accurate detection of magnetically labeled cells.",

keywords = "Biosensor, PDMS microchannel, flow cytometer, magnetic bead, magnetic tunnel junction",

author = "Selma Amara and Ride Bu and Meshal Alawein and Nouf Alsharif and Khan, {Mohammed Asadullah} and Yan Wen and Xixiang Zhang and Jurgen Kosel and Hossein Fariborzi",

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doi = "10.1109/MeMeA.2018.8438652",

language = "English (US)",

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series = "MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings",

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Amara, S, Bu, R, Alawein, M, Alsharif, N, Khan, MA, Wen, Y, Zhang, X, Kosel, J & Fariborzi, H 2018, Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer. in MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings., 8438652, MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings, Institute of Electrical and Electronics Engineers Inc., 13th IEEE International Symposium on Medical Measurements and Applications, MeMeA 2018, Rome, Italy, 06/11/18. https://doi.org/10.1109/MeMeA.2018.8438652

Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer. / Amara, Selma; Bu, Ride; Alawein, Meshal et al.
MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings. Institute of Electrical and Electronics Engineers Inc., 2018. 8438652 (MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Amara, Selma

AU - Bu, Ride

AU - Alawein, Meshal

AU - Alsharif, Nouf

AU - Khan, Mohammed Asadullah

AU - Wen, Yan

AU - Zhang, Xixiang

AU - Kosel, Jurgen

AU - Fariborzi, Hossein

PY - 2018/8/16

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N2 - Flow cytometers are important instruments for biological and biomedical analyses. These instruments are large and expensive, and researchers are continuously striving to come up with smaller, cheaper, and more energy-efficient flow cytometers. In this work, we present a highly-sensitive magnetic tunnel junction (MTJ) based flow cytometer. An externally magnetized magnetic beads labeling cells were placed above an MTJ sensor that can measure the stray field surrounding the beads. It was found that each time labeled cells pass through the sensitive area of the sensor, a peak of signal was observed. The results demonstrate a novel MTJ based flow cytometer design approach for accurate detection of magnetically labeled cells.

AB - Flow cytometers are important instruments for biological and biomedical analyses. These instruments are large and expensive, and researchers are continuously striving to come up with smaller, cheaper, and more energy-efficient flow cytometers. In this work, we present a highly-sensitive magnetic tunnel junction (MTJ) based flow cytometer. An externally magnetized magnetic beads labeling cells were placed above an MTJ sensor that can measure the stray field surrounding the beads. It was found that each time labeled cells pass through the sensitive area of the sensor, a peak of signal was observed. The results demonstrate a novel MTJ based flow cytometer design approach for accurate detection of magnetically labeled cells.

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KW - PDMS microchannel

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Amara S, Bu R, Alawein M, Alsharif N, Khan MA, Wen Y et al. Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer. In MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings. Institute of Electrical and Electronics Engineers Inc. 2018. 8438652. (MeMeA 2018 - 2018 IEEE International Symposium on Medical Measurements and Applications, Proceedings). doi: 10.1109/MeMeA.2018.8438652

Highly-Sensitive Magnetic Tunnel Junction Based Flow Cytometer

Abstract

Publication series

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Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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