Highly sensitive amperometric sensor for carbamazepine determination based on electrochemically reduced graphene oxide-single-walled carbon nanotube composite film

Binesh Unnikrishnan; Veerappan Mani; Shen Ming Chen

doi:10.1016/j.snb.2012.06.088

Highly sensitive amperometric sensor for carbamazepine determination based on electrochemically reduced graphene oxide-single-walled carbon nanotube composite film

Binesh Unnikrishnan, Veerappan Mani, Shen Ming Chen

Research output: Contribution to journal › Article › peer-review

91 Scopus citations

Abstract

We report a highly sensitive amperometric sensor for the determination of carbamazepine (CBZ) at an electrochemically reduced graphene oxide (ERGO) and single walled carbon nanotube (SWCNT) composite film modified glassy carbon electrode (GCE). The π-π stacking interactions between ERGO and SWCNT add good stability to the composite film which was confirmed by UV-visible and FTIR spectroscopy. Compared with SWCNT modified electrode, ERGO-SWCNT composite film modified electrode exhibits a 3.2 fold enhancement in peak current for CBZ oxidation. The proposed sensor detects CBZ as low as 29 nM and has a sensitivity of 5.1076 μA μM -1 cm -2 in the linear range of 50 nM to 3 μM. The practicality of this sensor has been evaluated by the determination of CBZ from Tegratol tablets showing good sensitivity and linearity. © 2012 Elsevier B.V.

Original language	English (US)
Pages (from-to)	274-280
Number of pages	7
Journal	Sensors and Actuators, B: Chemical
Volume	173
DOIs	https://doi.org/10.1016/j.snb.2012.06.088
State	Published - Oct 1 2012
Externally published	Yes

Bibliographical note

Generated from Scopus record by KAUST IRTS on 2023-09-21

ASJC Scopus subject areas

Materials Chemistry
Instrumentation
Surfaces, Coatings and Films
Metals and Alloys
Electronic, Optical and Magnetic Materials
Electrical and Electronic Engineering
Condensed Matter Physics

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title = "Highly sensitive amperometric sensor for carbamazepine determination based on electrochemically reduced graphene oxide-single-walled carbon nanotube composite film",

abstract = "We report a highly sensitive amperometric sensor for the determination of carbamazepine (CBZ) at an electrochemically reduced graphene oxide (ERGO) and single walled carbon nanotube (SWCNT) composite film modified glassy carbon electrode (GCE). The π-π stacking interactions between ERGO and SWCNT add good stability to the composite film which was confirmed by UV-visible and FTIR spectroscopy. Compared with SWCNT modified electrode, ERGO-SWCNT composite film modified electrode exhibits a 3.2 fold enhancement in peak current for CBZ oxidation. The proposed sensor detects CBZ as low as 29 nM and has a sensitivity of 5.1076 μA μM -1 cm -2 in the linear range of 50 nM to 3 μM. The practicality of this sensor has been evaluated by the determination of CBZ from Tegratol tablets showing good sensitivity and linearity. {\textcopyright} 2012 Elsevier B.V.",

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AU - Unnikrishnan, Binesh

AU - Mani, Veerappan

AU - Chen, Shen Ming

N1 - Generated from Scopus record by KAUST IRTS on 2023-09-21

PY - 2012/10/1

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N2 - We report a highly sensitive amperometric sensor for the determination of carbamazepine (CBZ) at an electrochemically reduced graphene oxide (ERGO) and single walled carbon nanotube (SWCNT) composite film modified glassy carbon electrode (GCE). The π-π stacking interactions between ERGO and SWCNT add good stability to the composite film which was confirmed by UV-visible and FTIR spectroscopy. Compared with SWCNT modified electrode, ERGO-SWCNT composite film modified electrode exhibits a 3.2 fold enhancement in peak current for CBZ oxidation. The proposed sensor detects CBZ as low as 29 nM and has a sensitivity of 5.1076 μA μM -1 cm -2 in the linear range of 50 nM to 3 μM. The practicality of this sensor has been evaluated by the determination of CBZ from Tegratol tablets showing good sensitivity and linearity. © 2012 Elsevier B.V.

AB - We report a highly sensitive amperometric sensor for the determination of carbamazepine (CBZ) at an electrochemically reduced graphene oxide (ERGO) and single walled carbon nanotube (SWCNT) composite film modified glassy carbon electrode (GCE). The π-π stacking interactions between ERGO and SWCNT add good stability to the composite film which was confirmed by UV-visible and FTIR spectroscopy. Compared with SWCNT modified electrode, ERGO-SWCNT composite film modified electrode exhibits a 3.2 fold enhancement in peak current for CBZ oxidation. The proposed sensor detects CBZ as low as 29 nM and has a sensitivity of 5.1076 μA μM -1 cm -2 in the linear range of 50 nM to 3 μM. The practicality of this sensor has been evaluated by the determination of CBZ from Tegratol tablets showing good sensitivity and linearity. © 2012 Elsevier B.V.

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JO - Sensors and Actuators, B: Chemical

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Highly sensitive amperometric sensor for carbamazepine determination based on electrochemically reduced graphene oxide-single-walled carbon nanotube composite film

Abstract

Bibliographical note

ASJC Scopus subject areas

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