Hepatitis C Virus: Virology and Genotypes

Ahmed Abdelaziz

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations


Hepatitis C virus (HCV) is a major causative agent of chronic liver disease worldwide. HCV is characterized by genetic heterogeneity, with at least six genotypes identified. The geographic distribution of genotypes has shown variations in different parts of the world over the past decade because of variations in population structure, immigration, and routes of transmission. Genotype differences are of epidemiologic interest and help the study of viral transmission dynamics to trace the source of HCV infection in a given population. HCV genotypes are also of considerable clinical importance because they affect response to antiviral therapy and represent a challenging obstacle for vaccine development.
Original languageEnglish (US)
Title of host publicationHepatitis C in Developing Countries
PublisherElsevier BV
Number of pages9
ISBN (Print)9780128032336
StatePublished - Dec 1 2017

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01


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