Gold nanodisc arrays as near infrared metal-enhanced fluorescence platforms with tuneable enhancement factors

J. Pang; I. G. Theodorou; A. Centeno; P. K. Petrov; N. M. Alford; M. P. Ryan; F. Xie

doi:10.1039/c6tc04965f

Gold nanodisc arrays as near infrared metal-enhanced fluorescence platforms with tuneable enhancement factors

J. Pang, I. G. Theodorou, A. Centeno, P. K. Petrov, N. M. Alford, M. P. Ryan, F. Xie

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Metal enhanced fluorescence (MEF) is a physical effect through which the near-field interaction of fluorophores with metallic nanoparticles can lead to large fluorescence enhancement. MEF can be exploited in many fluorescence-based biomedical applications, with potentially significant improvement in detection sensitivity and contrast enhancement. Offering lower autofluorescence and minimal photoinduced damage, the development of effective and multifunctional MEF platforms in the near-infrared (NIR) region, is particularly desirable. In this work, the enhancement of NIR fluorescence caused by interaction with regular arrays of cylindrical gold (Au) nanoparticles (nanodiscs), fabricated through nanosphere lithography, is reported. Significant MEF of up to 235 times is obtained, with tuneable enhancement factors. The effect of array structure on fluorescence enhancement is investigated by semi-quantitatively de-convoluting excitation enhancement from emission enhancement, and modelling the local electric field enhancement. By considering arrays of Au nanodiscs with the same extinction maximum, it is shown that the excitation enhancement, due to increased electric field, is not significantly different for the particle sizes and separation distances considered. Rather, it is seen that the emission from the fluorophore is strongly enhanced, and is dependent on the topography, in particular particle size. The results show that the structural characteristics of Au nanodisc arrays can be manipulated to tune their enhancement factor, and hence their sensitivity.

Original language	English (US)
Pages (from-to)	917-925
Number of pages	9
Journal	J. Mater. Chem. C
Volume	5
Issue number	4
DOIs	https://doi.org/10.1039/c6tc04965f
State	Published - 2017
Externally published	Yes

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: J. P. and P. K. P. acknowledge King Abdulla University for Science and Technology's (KAUST) AEA Collaborative Research Program. I. G. T., A. C. and F. X. are supported by a British Council Newton Grant (#216239013). P. K. P., M. P. R., N. M. A. and F. X. acknowledge an EPSRC programme grant (EP/G060940/1). A. C. is also supported by a FRGS Grant (FRGS/2/2013/SG02/UTM/02/3) from the Malaysian Ministry of Education.
This publication acknowledges KAUST support, but has no KAUST affiliated authors.

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@article{e9282eceb7414852ba400e23e03fb3ac,

title = "Gold nanodisc arrays as near infrared metal-enhanced fluorescence platforms with tuneable enhancement factors",

abstract = "Metal enhanced fluorescence (MEF) is a physical effect through which the near-field interaction of fluorophores with metallic nanoparticles can lead to large fluorescence enhancement. MEF can be exploited in many fluorescence-based biomedical applications, with potentially significant improvement in detection sensitivity and contrast enhancement. Offering lower autofluorescence and minimal photoinduced damage, the development of effective and multifunctional MEF platforms in the near-infrared (NIR) region, is particularly desirable. In this work, the enhancement of NIR fluorescence caused by interaction with regular arrays of cylindrical gold (Au) nanoparticles (nanodiscs), fabricated through nanosphere lithography, is reported. Significant MEF of up to 235 times is obtained, with tuneable enhancement factors. The effect of array structure on fluorescence enhancement is investigated by semi-quantitatively de-convoluting excitation enhancement from emission enhancement, and modelling the local electric field enhancement. By considering arrays of Au nanodiscs with the same extinction maximum, it is shown that the excitation enhancement, due to increased electric field, is not significantly different for the particle sizes and separation distances considered. Rather, it is seen that the emission from the fluorophore is strongly enhanced, and is dependent on the topography, in particular particle size. The results show that the structural characteristics of Au nanodisc arrays can be manipulated to tune their enhancement factor, and hence their sensitivity.",

author = "J. Pang and Theodorou, {I. G.} and A. Centeno and Petrov, {P. K.} and Alford, {N. M.} and Ryan, {M. P.} and F. Xie",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: J. P. and P. K. P. acknowledge King Abdulla University for Science and Technology's (KAUST) AEA Collaborative Research Program. I. G. T., A. C. and F. X. are supported by a British Council Newton Grant (#216239013). P. K. P., M. P. R., N. M. A. and F. X. acknowledge an EPSRC programme grant (EP/G060940/1). A. C. is also supported by a FRGS Grant (FRGS/2/2013/SG02/UTM/02/3) from the Malaysian Ministry of Education. This publication acknowledges KAUST support, but has no KAUST affiliated authors.",

year = "2017",

doi = "10.1039/c6tc04965f",

language = "English (US)",

volume = "5",

pages = "917--925",

journal = "J. Mater. Chem. C",

issn = "2050-7526",

publisher = "Royal Society of Chemistry",

number = "4",

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TY - JOUR

T1 - Gold nanodisc arrays as near infrared metal-enhanced fluorescence platforms with tuneable enhancement factors

AU - Pang, J.

AU - Theodorou, I. G.

AU - Centeno, A.

AU - Petrov, P. K.

AU - Alford, N. M.

AU - Ryan, M. P.

AU - Xie, F.

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: J. P. and P. K. P. acknowledge King Abdulla University for Science and Technology's (KAUST) AEA Collaborative Research Program. I. G. T., A. C. and F. X. are supported by a British Council Newton Grant (#216239013). P. K. P., M. P. R., N. M. A. and F. X. acknowledge an EPSRC programme grant (EP/G060940/1). A. C. is also supported by a FRGS Grant (FRGS/2/2013/SG02/UTM/02/3) from the Malaysian Ministry of Education. This publication acknowledges KAUST support, but has no KAUST affiliated authors.

PY - 2017

Y1 - 2017

N2 - Metal enhanced fluorescence (MEF) is a physical effect through which the near-field interaction of fluorophores with metallic nanoparticles can lead to large fluorescence enhancement. MEF can be exploited in many fluorescence-based biomedical applications, with potentially significant improvement in detection sensitivity and contrast enhancement. Offering lower autofluorescence and minimal photoinduced damage, the development of effective and multifunctional MEF platforms in the near-infrared (NIR) region, is particularly desirable. In this work, the enhancement of NIR fluorescence caused by interaction with regular arrays of cylindrical gold (Au) nanoparticles (nanodiscs), fabricated through nanosphere lithography, is reported. Significant MEF of up to 235 times is obtained, with tuneable enhancement factors. The effect of array structure on fluorescence enhancement is investigated by semi-quantitatively de-convoluting excitation enhancement from emission enhancement, and modelling the local electric field enhancement. By considering arrays of Au nanodiscs with the same extinction maximum, it is shown that the excitation enhancement, due to increased electric field, is not significantly different for the particle sizes and separation distances considered. Rather, it is seen that the emission from the fluorophore is strongly enhanced, and is dependent on the topography, in particular particle size. The results show that the structural characteristics of Au nanodisc arrays can be manipulated to tune their enhancement factor, and hence their sensitivity.

AB - Metal enhanced fluorescence (MEF) is a physical effect through which the near-field interaction of fluorophores with metallic nanoparticles can lead to large fluorescence enhancement. MEF can be exploited in many fluorescence-based biomedical applications, with potentially significant improvement in detection sensitivity and contrast enhancement. Offering lower autofluorescence and minimal photoinduced damage, the development of effective and multifunctional MEF platforms in the near-infrared (NIR) region, is particularly desirable. In this work, the enhancement of NIR fluorescence caused by interaction with regular arrays of cylindrical gold (Au) nanoparticles (nanodiscs), fabricated through nanosphere lithography, is reported. Significant MEF of up to 235 times is obtained, with tuneable enhancement factors. The effect of array structure on fluorescence enhancement is investigated by semi-quantitatively de-convoluting excitation enhancement from emission enhancement, and modelling the local electric field enhancement. By considering arrays of Au nanodiscs with the same extinction maximum, it is shown that the excitation enhancement, due to increased electric field, is not significantly different for the particle sizes and separation distances considered. Rather, it is seen that the emission from the fluorophore is strongly enhanced, and is dependent on the topography, in particular particle size. The results show that the structural characteristics of Au nanodisc arrays can be manipulated to tune their enhancement factor, and hence their sensitivity.

UR - http://hdl.handle.net/10754/623550

UR - http://xlink.rsc.org/?DOI=C6TC04965F

UR - http://www.scopus.com/inward/record.url?scp=85010850457&partnerID=8YFLogxK

U2 - 10.1039/c6tc04965f

DO - 10.1039/c6tc04965f

M3 - Article

SN - 2050-7526

VL - 5

SP - 917

EP - 925

JO - J. Mater. Chem. C

JF - J. Mater. Chem. C

IS - 4

ER -

Gold nanodisc arrays as near infrared metal-enhanced fluorescence platforms with tuneable enhancement factors

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