Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery

Saher Rhamani; Arnaud Chaix; Dina Aggad; PHUONG HOANG; Basem Moosa; Marcel Garcia; Magali Gary-Bobo; Clarence Charnay; Abdulaziz Almalik; Jean-Olivier Durand; Niveen M. Khashab

doi:10.1039/c7me00058h

Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery

Saher Rhamani, Arnaud Chaix, Dina Aggad, PHUONG HOANG, Basem Moosa, Marcel Garcia, Magali Gary-Bobo, Clarence Charnay, Abdulaziz Almalik, Jean-Olivier Durand, Niveen M. Khashab

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7 Scopus citations

Abstract

The synthesis of gold core degradable mesoporous organosilica shell nanoparticles is described. The nanopaticles were very efficient for two-photon luminescence imaging of cancer cells and for in vitro gemcitabine monophosphate delivery, allowing promising theranostic applications in the nanomedicine field.

Original language	English (US)
Pages (from-to)	380-383
Number of pages	4
Journal	Mol. Syst. Des. Eng.
Volume	2
Issue number	4
DOIs	https://doi.org/10.1039/c7me00058h
State	Published - Sep 12 2017

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: We thank King Abdullah University for science and Technology (KAUST) and King Abdulaziz City of Science and Technology (KACST) for the financial support. The Erasmus Mundus grant for S.R. is gratefully acknowledged. The rio imaging platform is acknowledged for technical assistance. The authors thank Dr. G. Mouchaham for Adsorption/Desorption of Nitrogen.

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10.1039/c7me00058h

https://repository.kaust.edu.sa/bitstream/10754/625494/1/c7me00058h.pdf

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title = "Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery",

abstract = "The synthesis of gold core degradable mesoporous organosilica shell nanoparticles is described. The nanopaticles were very efficient for two-photon luminescence imaging of cancer cells and for in vitro gemcitabine monophosphate delivery, allowing promising theranostic applications in the nanomedicine field.",

author = "Saher Rhamani and Arnaud Chaix and Dina Aggad and PHUONG HOANG and Basem Moosa and Marcel Garcia and Magali Gary-Bobo and Clarence Charnay and Abdulaziz Almalik and Jean-Olivier Durand and Khashab, {Niveen M.}",

note = "KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: We thank King Abdullah University for science and Technology (KAUST) and King Abdulaziz City of Science and Technology (KACST) for the financial support. The Erasmus Mundus grant for S.R. is gratefully acknowledged. The rio imaging platform is acknowledged for technical assistance. The authors thank Dr. G. Mouchaham for Adsorption/Desorption of Nitrogen.",

year = "2017",

month = sep,

day = "12",

doi = "10.1039/c7me00058h",

language = "English (US)",

volume = "2",

pages = "380--383",

journal = "Mol. Syst. Des. Eng.",

issn = "2058-9689",

publisher = "Royal Society of Chemistry",

number = "4",

}

TY - JOUR

T1 - Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery

AU - Rhamani, Saher

AU - Chaix, Arnaud

AU - Aggad, Dina

AU - HOANG, PHUONG

AU - Moosa, Basem

AU - Garcia, Marcel

AU - Gary-Bobo, Magali

AU - Charnay, Clarence

AU - Almalik, Abdulaziz

AU - Durand, Jean-Olivier

AU - Khashab, Niveen M.

N1 - KAUST Repository Item: Exported on 2020-10-01 Acknowledgements: We thank King Abdullah University for science and Technology (KAUST) and King Abdulaziz City of Science and Technology (KACST) for the financial support. The Erasmus Mundus grant for S.R. is gratefully acknowledged. The rio imaging platform is acknowledged for technical assistance. The authors thank Dr. G. Mouchaham for Adsorption/Desorption of Nitrogen.

PY - 2017/9/12

Y1 - 2017/9/12

N2 - The synthesis of gold core degradable mesoporous organosilica shell nanoparticles is described. The nanopaticles were very efficient for two-photon luminescence imaging of cancer cells and for in vitro gemcitabine monophosphate delivery, allowing promising theranostic applications in the nanomedicine field.

AB - The synthesis of gold core degradable mesoporous organosilica shell nanoparticles is described. The nanopaticles were very efficient for two-photon luminescence imaging of cancer cells and for in vitro gemcitabine monophosphate delivery, allowing promising theranostic applications in the nanomedicine field.

UR - http://hdl.handle.net/10754/625494

UR - http://pubs.rsc.org/en/Content/ArticleLanding/2017/ME/C7ME00058H#!divAbstract

UR - http://www.scopus.com/inward/record.url?scp=85045473935&partnerID=8YFLogxK

U2 - 10.1039/c7me00058h

DO - 10.1039/c7me00058h

M3 - Article

SN - 2058-9689

VL - 2

SP - 380

EP - 383

JO - Mol. Syst. Des. Eng.

JF - Mol. Syst. Des. Eng.

IS - 4

ER -

Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery

Abstract

Bibliographical note

UN SDGs

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