Glycogen: A Trojan horse for neurons

Pierre J. Magistretti*, Igor Allaman

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

30 Scopus citations

Abstract

Neural activity leads to the mobilization of energy from glycogen in astrocytes. A new paper reports that neurons have an ambivalent relationship with glycogen: they can synthesize it themselves, but that synthesis induces apoptosis. Presumably for this reason, neurons normally inhibit glycogen synthesis through two redundant pathways.

Original languageEnglish (US)
Pages (from-to)1341-1342
Number of pages2
JournalNature Neuroscience
Volume10
Issue number11
DOIs
StatePublished - Nov 2007
Externally publishedYes

ASJC Scopus subject areas

  • General Neuroscience

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