TY - JOUR
T1 - Gibberellic acid and cGMP-dependent transcriptional regulation in arabidopsis thaliana
AU - Bastian, René
AU - Dawe, Adam Sean
AU - Meier, Stuart Kurt
AU - Ludidi, Ndiko N.
AU - Bajic, Vladimir B.
AU - Gehring, Christoph A
N1 - KAUST Repository Item: Exported on 2020-10-01
PY - 2014/10/31
Y1 - 2014/10/31
N2 - An ever increasing amount of transcriptomic data and analysis tools provide novel insight into complex responses of biological systems. Given these resources we have undertaken to review aspects of transcriptional regulation in response to the plant hormone gibberellic acid (GA) and its second messenger guanosine 3',5'-cyclic monophosphate (cGMP) in Arabidopsis thaliana, both wild type and selected mutants. Evidence suggests enrichment of GA-responsive (GARE) elements in promoters of genes that are transcriptionally upregulated in response to cGMP but downregulated in a GA insensitive mutant (ga1-3). In contrast, in the genes upregulated in the mutant, no enrichment in the GARE is observed suggesting that GARE motifs are diagnostic for GA-induced and cGMP-dependent transcriptional upregulation. Further, we review how expression studies of GA-dependent transcription factors and transcriptional networks based on common promoter signatures derived from ab initio analyses can contribute to our understanding of plant responses at the systems level. © 2010 Landes Bioscience.
AB - An ever increasing amount of transcriptomic data and analysis tools provide novel insight into complex responses of biological systems. Given these resources we have undertaken to review aspects of transcriptional regulation in response to the plant hormone gibberellic acid (GA) and its second messenger guanosine 3',5'-cyclic monophosphate (cGMP) in Arabidopsis thaliana, both wild type and selected mutants. Evidence suggests enrichment of GA-responsive (GARE) elements in promoters of genes that are transcriptionally upregulated in response to cGMP but downregulated in a GA insensitive mutant (ga1-3). In contrast, in the genes upregulated in the mutant, no enrichment in the GARE is observed suggesting that GARE motifs are diagnostic for GA-induced and cGMP-dependent transcriptional upregulation. Further, we review how expression studies of GA-dependent transcription factors and transcriptional networks based on common promoter signatures derived from ab initio analyses can contribute to our understanding of plant responses at the systems level. © 2010 Landes Bioscience.
UR - http://hdl.handle.net/10754/561498
UR - http://www.tandfonline.com/doi/abs/10.4161/psb.5.3.10718
UR - http://www.scopus.com/inward/record.url?scp=77954897153&partnerID=8YFLogxK
U2 - 10.4161/psb.5.3.10718
DO - 10.4161/psb.5.3.10718
M3 - Article
C2 - 20118660
SN - 1559-2316
VL - 5
SP - 224
EP - 232
JO - Plant signaling & behavior
JF - Plant signaling & behavior
IS - 3
ER -