Gating pluripotency via nuclear pores

Jiping Yang, Ning Cai, Fei Yi, Guang Hui Liu*, Jing Qu, Juan Carlos Izpisua Belmonte

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

In recent years, growing evidence has pointed to the interesting idea that pluripotency might be regulated by a nuclear-pore-coordinated network that controls the level of pluripotency factors in the nucleus. A thorough understanding of this process might improve our comprehension of cell pluripotency and differentiation during embryogenesis, as well as aiding the development of novel models for studying human diseases.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalTrends in Molecular Medicine
Volume20
Issue number1
DOIs
StatePublished - Jan 2014
Externally publishedYes

Bibliographical note

Funding Information:
G.H.L. is supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA01020312), the National Basic Research Program of China (973 Program, 2014CB964600), the National Natural Science Foundation of China (NSFC) (81330008, 81271266, 31222039, and 31201111), the Thousand Young Talents program of China, the National Laboratory of Biomacromolecules, and the State Key Laboratory of Drug Research (SIMM1302KF-17). J.Q. is supported by the National Basic Research Program of China (973 Program, 2014CB910500) and NSFC (81371342). J.C.I.B. is supported by TERCEL-ISCIII-MINECO, CIBER, Fundacion Cellex, the G. Harold and Leila Y. Mathers Charitable Foundation, the Leona M. and Harry B. Helmsley Charitable Trust, The Glenn Foundation and the Ellison Medical Foundation.

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology

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