Functional Group Interconversion: Decarbonylative Borylation of Esters for the Synthesis of Organoboronates

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Abstract

A new and efficient nickel-catalyzed decarbonylative borylation reaction of carboxylic acid esters with bis(pinacolato)-diboron has been developed. This transformation allows access to structurally diverse aryl as well as alkenyl and alkyl boronate esters with high reactivity, broad substrate scope, and excellent functional-group tolerance. Further experiments show that this protocol can be carried out on a gram scale and applied to orthogonal synthetic strategies.
Original languageEnglish (US)
Pages (from-to)16787-16790
Number of pages4
JournalChemistry - A European Journal
Volume22
Issue number47
DOIs
StatePublished - Oct 11 2016

Bibliographical note

KAUST Repository Item: Exported on 2020-10-01
Acknowledgements: L.G. was supported by the China Scholarship Council.

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