Fluorescent ABC-Triblock Polymer Nanocarrier for Cisplatin Delivery to Cancer Cells.

Bhagyashree Kulkarni, Mehak Malhotra, Manickam Jayakannan

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Monitoring intracellular administration of non-luminescent anticancer drugs like cisplatin is a very challenging task in cancer research. Perylenebisimide (PBI) chromophore tagged fluorescent ABC-triblock polycaprolactone (PCL) nanoscaffold was engineered having carboxylic acid blocks for the chemical conjugation of cisplatin at the core and hydrophilic PEG blocks at the periphery. The amphiphilic ABC triblock Pt-prodrug was self-assembled into
Original languageEnglish (US)
JournalChemistry, an Asian journal
DOIs
StatePublished - Jan 10 2022

Bibliographical note

KAUST Repository Item: Exported on 2022-02-01
Acknowledgements: The authors thank research grant from Science and Engineering Research Board (SERB), Project No. CRG/2019/000496, New Delhi, INDIA. Mehak Malhotra thanks CSIR-SRF for fellowship. IISER Pune microscopy facilities are acknowledged.

ASJC Scopus subject areas

  • General Chemistry

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