Fluorescent ABC-Triblock Polymer Nanocarrier for Cisplatin Delivery to Cancer Cells.

Bhagyashree Kulkarni; Mehak Malhotra; Manickam Jayakannan

doi:10.1002/asia.202101337

Fluorescent ABC-Triblock Polymer Nanocarrier for Cisplatin Delivery to Cancer Cells.

Bhagyashree Kulkarni, Mehak Malhotra, Manickam Jayakannan

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Monitoring intracellular administration of non-luminescent anticancer drugs like cisplatin is a very challenging task in cancer research. Perylenebisimide (PBI) chromophore tagged fluorescent ABC-triblock polycaprolactone (PCL) nanoscaffold was engineered having carboxylic acid blocks for the chemical conjugation of cisplatin at the core and hydrophilic PEG blocks at the periphery. The amphiphilic ABC triblock Pt-prodrug was self-assembled into

Original language	English (US)
Journal	Chemistry, an Asian journal
DOIs	https://doi.org/10.1002/asia.202101337
State	Published - Jan 10 2022

Bibliographical note

KAUST Repository Item: Exported on 2022-02-01
Acknowledgements: The authors thank research grant from Science and Engineering Research Board (SERB), Project No. CRG/2019/000496, New Delhi, INDIA. Mehak Malhotra thanks CSIR-SRF for fellowship. IISER Pune microscopy facilities are acknowledged.

ASJC Scopus subject areas

General Chemistry

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10.1002/asia.202101337

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title = "Fluorescent ABC-Triblock Polymer Nanocarrier for Cisplatin Delivery to Cancer Cells.",

abstract = "Monitoring intracellular administration of non-luminescent anticancer drugs like cisplatin is a very challenging task in cancer research. Perylenebisimide (PBI) chromophore tagged fluorescent ABC-triblock polycaprolactone (PCL) nanoscaffold was engineered having carboxylic acid blocks for the chemical conjugation of cisplatin at the core and hydrophilic PEG blocks at the periphery. The amphiphilic ABC triblock Pt-prodrug was self-assembled into",

author = "Bhagyashree Kulkarni and Mehak Malhotra and Manickam Jayakannan",

note = "KAUST Repository Item: Exported on 2022-02-01 Acknowledgements: The authors thank research grant from Science and Engineering Research Board (SERB), Project No. CRG/2019/000496, New Delhi, INDIA. Mehak Malhotra thanks CSIR-SRF for fellowship. IISER Pune microscopy facilities are acknowledged.",

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AU - Kulkarni, Bhagyashree

AU - Malhotra, Mehak

AU - Jayakannan, Manickam

N1 - KAUST Repository Item: Exported on 2022-02-01 Acknowledgements: The authors thank research grant from Science and Engineering Research Board (SERB), Project No. CRG/2019/000496, New Delhi, INDIA. Mehak Malhotra thanks CSIR-SRF for fellowship. IISER Pune microscopy facilities are acknowledged.

PY - 2022/1/10

Y1 - 2022/1/10

N2 - Monitoring intracellular administration of non-luminescent anticancer drugs like cisplatin is a very challenging task in cancer research. Perylenebisimide (PBI) chromophore tagged fluorescent ABC-triblock polycaprolactone (PCL) nanoscaffold was engineered having carboxylic acid blocks for the chemical conjugation of cisplatin at the core and hydrophilic PEG blocks at the periphery. The amphiphilic ABC triblock Pt-prodrug was self-assembled into

AB - Monitoring intracellular administration of non-luminescent anticancer drugs like cisplatin is a very challenging task in cancer research. Perylenebisimide (PBI) chromophore tagged fluorescent ABC-triblock polycaprolactone (PCL) nanoscaffold was engineered having carboxylic acid blocks for the chemical conjugation of cisplatin at the core and hydrophilic PEG blocks at the periphery. The amphiphilic ABC triblock Pt-prodrug was self-assembled into

UR - http://hdl.handle.net/10754/675259

UR - https://onlinelibrary.wiley.com/doi/10.1002/asia.202101337

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DO - 10.1002/asia.202101337

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SN - 1861-4728

JO - Chemistry, an Asian journal

JF - Chemistry, an Asian journal

ER -

Fluorescent ABC-Triblock Polymer Nanocarrier for Cisplatin Delivery to Cancer Cells.

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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