First total synthesis of cryptomisrine

Erwan Arzel; Patrick Rocca; Francis Marsais; Alain Godard; Guy Quéguiner

doi:10.1016/S0040-4020(99)00715-2

First total synthesis of cryptomisrine

Erwan Arzel, Patrick Rocca^*, Francis Marsais, Alain Godard, Guy Quéguiner

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

The first total synthesis of cryptomisrine, a novel indolo[3,2- b]quinoline dimeric alkaloid from Cryptolepis sanguinolenta, is reported. The approach is based on a convergent methodology which involves a new halogen- dance reaction in quinoline series connected to a cross-coupling reaction.

Original language	English (US)
Pages (from-to)	12149-12156
Number of pages	8
Journal	Tetrahedron
Volume	55
Issue number	41
DOIs	https://doi.org/10.1016/S0040-4020(99)00715-2
State	Published - Oct 8 1999
Externally published	Yes

Keywords

Coupling reactions
Halogen and compounds
Metallation
Polycyclic compounds

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4020(99)00715-2

Cite this

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title = "First total synthesis of cryptomisrine",

abstract = "The first total synthesis of cryptomisrine, a novel indolo[3,2- b]quinoline dimeric alkaloid from Cryptolepis sanguinolenta, is reported. The approach is based on a convergent methodology which involves a new halogen- dance reaction in quinoline series connected to a cross-coupling reaction.",

keywords = "Coupling reactions, Halogen and compounds, Metallation, Polycyclic compounds",

author = "Erwan Arzel and Patrick Rocca and Francis Marsais and Alain Godard and Guy Qu{\'e}guiner",

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AU - Arzel, Erwan

AU - Rocca, Patrick

AU - Marsais, Francis

AU - Godard, Alain

AU - Quéguiner, Guy

PY - 1999/10/8

Y1 - 1999/10/8

N2 - The first total synthesis of cryptomisrine, a novel indolo[3,2- b]quinoline dimeric alkaloid from Cryptolepis sanguinolenta, is reported. The approach is based on a convergent methodology which involves a new halogen- dance reaction in quinoline series connected to a cross-coupling reaction.

AB - The first total synthesis of cryptomisrine, a novel indolo[3,2- b]quinoline dimeric alkaloid from Cryptolepis sanguinolenta, is reported. The approach is based on a convergent methodology which involves a new halogen- dance reaction in quinoline series connected to a cross-coupling reaction.

KW - Coupling reactions

KW - Halogen and compounds

KW - Metallation

KW - Polycyclic compounds

UR - http://www.scopus.com/inward/record.url?scp=0033536652&partnerID=8YFLogxK

U2 - 10.1016/S0040-4020(99)00715-2

DO - 10.1016/S0040-4020(99)00715-2

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SP - 12149

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JO - Tetrahedron

JF - Tetrahedron

IS - 41

ER -

First total synthesis of cryptomisrine

Abstract

Keywords

ASJC Scopus subject areas

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