First total synthesis of cryptomisrine

Erwan Arzel, Patrick Rocca*, Francis Marsais, Alain Godard, Guy Quéguiner

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    42 Scopus citations


    The first total synthesis of cryptomisrine, a novel indolo[3,2- b]quinoline dimeric alkaloid from Cryptolepis sanguinolenta, is reported. The approach is based on a convergent methodology which involves a new halogen- dance reaction in quinoline series connected to a cross-coupling reaction.

    Original languageEnglish (US)
    Pages (from-to)12149-12156
    Number of pages8
    Issue number41
    StatePublished - Oct 8 1999


    • Coupling reactions
    • Halogen and compounds
    • Metallation
    • Polycyclic compounds

    ASJC Scopus subject areas

    • Biochemistry
    • Drug Discovery
    • Organic Chemistry


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