Fast, efficient, mild, and metal-free synthesis of pyrroles by domino reactions in water

Magnus Rueping; Alejandro Parra

doi:10.1021/ol102247n

Fast, efficient, mild, and metal-free synthesis of pyrroles by domino reactions in water

Magnus Rueping^*, Alejandro Parra

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Abstract

(E)-β-Bromonitrostyrenes react with enaminones in water to afford pyrroles in excellent yields. The domino reaction constitutes a new, mild, and environmentally benign process for the fast and efficient synthesis of diverse pyrroles.

Original language	English (US)
Pages (from-to)	5281-5283
Number of pages	3
Journal	Organic Letters
Volume	12
Issue number	22
DOIs	https://doi.org/10.1021/ol102247n
State	Published - Nov 19 2010
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol102247n

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title = "Fast, efficient, mild, and metal-free synthesis of pyrroles by domino reactions in water",

abstract = "(E)-β-Bromonitrostyrenes react with enaminones in water to afford pyrroles in excellent yields. The domino reaction constitutes a new, mild, and environmentally benign process for the fast and efficient synthesis of diverse pyrroles.",

author = "Magnus Rueping and Alejandro Parra",

year = "2010",

month = nov,

day = "19",

doi = "10.1021/ol102247n",

language = "English (US)",

volume = "12",

pages = "5281--5283",

journal = "Organic Letters",

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T1 - Fast, efficient, mild, and metal-free synthesis of pyrroles by domino reactions in water

AU - Rueping, Magnus

AU - Parra, Alejandro

PY - 2010/11/19

Y1 - 2010/11/19

N2 - (E)-β-Bromonitrostyrenes react with enaminones in water to afford pyrroles in excellent yields. The domino reaction constitutes a new, mild, and environmentally benign process for the fast and efficient synthesis of diverse pyrroles.

AB - (E)-β-Bromonitrostyrenes react with enaminones in water to afford pyrroles in excellent yields. The domino reaction constitutes a new, mild, and environmentally benign process for the fast and efficient synthesis of diverse pyrroles.

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U2 - 10.1021/ol102247n

DO - 10.1021/ol102247n

M3 - Article

C2 - 20979413

AN - SCOPUS:78449271377

SN - 1523-7060

VL - 12

SP - 5281

EP - 5283

JO - Organic Letters

JF - Organic Letters

IS - 22

ER -

Fast, efficient, mild, and metal-free synthesis of pyrroles by domino reactions in water

Abstract

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