Fabrication of thulium metal–organic frameworks based smartphone sensor towards arsenical feed additive drug detection: Applicable in food safety analysis

Sathishkumar Chinnapaiyan; Umamaheswari Rajaji; Shen Ming Chen; Ting Yu Liu; Jose De Oliveira Filho; Yo Shiuan Chang

doi:10.1016/j.electacta.2021.139487

Fabrication of thulium metal–organic frameworks based smartphone sensor towards arsenical feed additive drug detection: Applicable in food safety analysis

Sathishkumar Chinnapaiyan, Umamaheswari Rajaji, Shen Ming Chen, Ting Yu Liu, Jose De Oliveira Filho, Yo Shiuan Chang

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

A portable sensor is needed for the quick screening of additives in food samples, to ensure food safety. The consumption of roxarsone (ROX) contaminated meat increases arsenic toxicity, risk of cancer and neurodegenerative diseases. In this research work, we report the synthesis of thulium (III)-benzene 1,3,5-tricarboxylic acid-based metal-organic framework (Tm-BTC MOF) and its use as an excellent electrocatalyst for the determination of ROX at point-of-care. A hydrothermal procedure was developed for the synthesis of Tm-BTC MOF using a single polarity solvent. A Tm-BTC MOF modified electrode was fabricated and its electrocatalytic sensing ability towards ROX was explored. Three kinds of special chemical interactions form a special affinity between ROX and Tm-BTC MOF. In association with differential pulse voltammetry, the Tm-BTC MOF/GCE showed a low detection limit of 100 pM. The Tm-BTC MOF modified electrode was integrated into a portable sensing device via coupling it with a miniaturized potentiostat (KAUSTat) operated wirelessly by a smartphone. The developed smartphone-based sensor was successful in measuring ROX not only in lab samples but also in real (spiked) food samples. The method can be suitable for on-site testing of food quality and safety in resource-limited settings.

Original language	English (US)
Pages (from-to)	139487
Journal	Electrochimica Acta
Volume	401
DOIs	https://doi.org/10.1016/j.electacta.2021.139487
State	Published - Oct 26 2021

Bibliographical note

KAUST Repository Item: Exported on 2021-11-16
Acknowledgements: The authors gratefully acknowledge the financial support of the Ministry of Science and Technology, MOST 110-2221-E-131-009, Taiwan and Research Centre for Intelligent Medical Devices of Ming Chi University of Technology, Taiwan and King Abdullah University of Science and Technology (KAUST), Saudi Arabia.

ASJC Scopus subject areas

General Chemical Engineering
Electrochemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.electacta.2021.139487

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title = "Fabrication of thulium metal–organic frameworks based smartphone sensor towards arsenical feed additive drug detection: Applicable in food safety analysis",

abstract = "A portable sensor is needed for the quick screening of additives in food samples, to ensure food safety. The consumption of roxarsone (ROX) contaminated meat increases arsenic toxicity, risk of cancer and neurodegenerative diseases. In this research work, we report the synthesis of thulium (III)-benzene 1,3,5-tricarboxylic acid-based metal-organic framework (Tm-BTC MOF) and its use as an excellent electrocatalyst for the determination of ROX at point-of-care. A hydrothermal procedure was developed for the synthesis of Tm-BTC MOF using a single polarity solvent. A Tm-BTC MOF modified electrode was fabricated and its electrocatalytic sensing ability towards ROX was explored. Three kinds of special chemical interactions form a special affinity between ROX and Tm-BTC MOF. In association with differential pulse voltammetry, the Tm-BTC MOF/GCE showed a low detection limit of 100 pM. The Tm-BTC MOF modified electrode was integrated into a portable sensing device via coupling it with a miniaturized potentiostat (KAUSTat) operated wirelessly by a smartphone. The developed smartphone-based sensor was successful in measuring ROX not only in lab samples but also in real (spiked) food samples. The method can be suitable for on-site testing of food quality and safety in resource-limited settings.",

author = "Sathishkumar Chinnapaiyan and Umamaheswari Rajaji and Chen, {Shen Ming} and Liu, {Ting Yu} and {De Oliveira Filho}, Jose and Chang, {Yo Shiuan}",

note = "KAUST Repository Item: Exported on 2021-11-16 Acknowledgements: The authors gratefully acknowledge the financial support of the Ministry of Science and Technology, MOST 110-2221-E-131-009, Taiwan and Research Centre for Intelligent Medical Devices of Ming Chi University of Technology, Taiwan and King Abdullah University of Science and Technology (KAUST), Saudi Arabia.",

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AU - Rajaji, Umamaheswari

AU - Chen, Shen Ming

AU - Liu, Ting Yu

AU - De Oliveira Filho, Jose

AU - Chang, Yo Shiuan

N1 - KAUST Repository Item: Exported on 2021-11-16 Acknowledgements: The authors gratefully acknowledge the financial support of the Ministry of Science and Technology, MOST 110-2221-E-131-009, Taiwan and Research Centre for Intelligent Medical Devices of Ming Chi University of Technology, Taiwan and King Abdullah University of Science and Technology (KAUST), Saudi Arabia.

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Y1 - 2021/10/26

N2 - A portable sensor is needed for the quick screening of additives in food samples, to ensure food safety. The consumption of roxarsone (ROX) contaminated meat increases arsenic toxicity, risk of cancer and neurodegenerative diseases. In this research work, we report the synthesis of thulium (III)-benzene 1,3,5-tricarboxylic acid-based metal-organic framework (Tm-BTC MOF) and its use as an excellent electrocatalyst for the determination of ROX at point-of-care. A hydrothermal procedure was developed for the synthesis of Tm-BTC MOF using a single polarity solvent. A Tm-BTC MOF modified electrode was fabricated and its electrocatalytic sensing ability towards ROX was explored. Three kinds of special chemical interactions form a special affinity between ROX and Tm-BTC MOF. In association with differential pulse voltammetry, the Tm-BTC MOF/GCE showed a low detection limit of 100 pM. The Tm-BTC MOF modified electrode was integrated into a portable sensing device via coupling it with a miniaturized potentiostat (KAUSTat) operated wirelessly by a smartphone. The developed smartphone-based sensor was successful in measuring ROX not only in lab samples but also in real (spiked) food samples. The method can be suitable for on-site testing of food quality and safety in resource-limited settings.

AB - A portable sensor is needed for the quick screening of additives in food samples, to ensure food safety. The consumption of roxarsone (ROX) contaminated meat increases arsenic toxicity, risk of cancer and neurodegenerative diseases. In this research work, we report the synthesis of thulium (III)-benzene 1,3,5-tricarboxylic acid-based metal-organic framework (Tm-BTC MOF) and its use as an excellent electrocatalyst for the determination of ROX at point-of-care. A hydrothermal procedure was developed for the synthesis of Tm-BTC MOF using a single polarity solvent. A Tm-BTC MOF modified electrode was fabricated and its electrocatalytic sensing ability towards ROX was explored. Three kinds of special chemical interactions form a special affinity between ROX and Tm-BTC MOF. In association with differential pulse voltammetry, the Tm-BTC MOF/GCE showed a low detection limit of 100 pM. The Tm-BTC MOF modified electrode was integrated into a portable sensing device via coupling it with a miniaturized potentiostat (KAUSTat) operated wirelessly by a smartphone. The developed smartphone-based sensor was successful in measuring ROX not only in lab samples but also in real (spiked) food samples. The method can be suitable for on-site testing of food quality and safety in resource-limited settings.

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JO - Electrochimica Acta

JF - Electrochimica Acta

ER -

Fabrication of thulium metal–organic frameworks based smartphone sensor towards arsenical feed additive drug detection: Applicable in food safety analysis

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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