Exploring the Potential Molecular Mechanisms of Interactions between a Probiotic Consortium and Its Coral Host

Phillipe M. Rosado, Pedro M. Cardoso, João G. Rosado, Júnia Schultz, Ulisses Nunes da Rocha, Tina Keller-Costa, Raquel S. Peixoto*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Beneficial microorganisms for corals (BMCs) have been demonstrated to be effective probiotics to alleviate bleaching and mitigate coral mortality in vivo. The selection of putative BMCs is traditionally performed manually, using an array of biochemical and molecular tests for putative BMC traits. We present a comprehensive genetic survey of BMC traits using a genome-based framework for the identification of alternative mechanisms that can be used for future in silico selection of BMC strains. We identify exclusive BMC traits associated with specific strains and propose new BMC mechanisms, such as the synthesis of glycine betaine and ectoines. Our roadmap facilitates the selection of BMC strains while increasing the array of genetic targets that can be included in the selection of putative BMC strains to be tested as coral probiotics.

Original languageEnglish (US)
JournalmSystems
Volume8
Issue number1
DOIs
StatePublished - Jan 2023

Bibliographical note

Funding Information:
This work was supported by grants FCC/1/1973-51-01, REI/1/4984-01, and BAS/1/ 1095-01-01 from King Abdullah University of Science and Technology (R.S.P.).

Publisher Copyright:
Copyright © 2023 Rosado et al.

Keywords

  • beneficial microorganisms for corals (BMCs)
  • BMCs
  • coral probiotics
  • genomes
  • holobiont
  • mechanisms
  • molecular interactions
  • probiotics
  • symbiosis

ASJC Scopus subject areas

  • Microbiology
  • Physiology
  • Biochemistry
  • Ecology, Evolution, Behavior and Systematics
  • Modeling and Simulation
  • Molecular Biology
  • Genetics
  • Computer Science Applications

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