TY - JOUR
T1 - Exploring nature's hidden treasure
T2 - Unraveling the untapped phytochemical and pharmacological potentials of Clinopodium vulgare L. – A hidden gem in the Lamiaceae family
AU - Qureshi, Kamal Ahmad
AU - Parvez, Adil
AU - Uzzaman Khan, Mohd Masih
AU - Aspatwar, Ashok
AU - Atiya, Akhtar
AU - Elhassan, Gamal Osman
AU - Khan, Riyaz Ahmed
AU - Erattil Ahammed, Shakkeela Yusuf
AU - Khan, Wasi Uzzaman
AU - Jaremko, Mariusz
N1 - Publisher Copyright:
© 2024 The Authors
PY - 2024/1/30
Y1 - 2024/1/30
N2 - Folk medicine, rooted in historical practice, has long been used for medicinal purposes, emphasizing the need to ensure the safety, quality, and efficacy of herbal medicines. This imperative has grown over time, prompting collaborative efforts to document historical records and preserve invaluable knowledge of medicinal plants. The Lamiaceae (Labiatae) family, renowned for its rich assortment of medicinal plants characterized by high concentrations of volatile oils, stands out in this regard. This review focuses on Clinopodium vulgare (C. vulgare) L., commonly known as wild basil or basil thyme, a significant species within the Lamiaceae family found across diverse global regions. C. vulgare boasts a storied history of application in treating various ailments, such as gastric ulcers, diabetes, and inflammation, dating back to ancient times. Rigorous research has substantiated its pharmacological properties, revealing its antioxidant, antiviral, antibacterial, anti-inflammatory, anticancer, antihypertensive, and enzyme-inhibitory effects. This comprehensive review provides an insightful overview of the Lamiaceae family, elucidates the extraction methods employed to obtain medicinal compounds, explores the phytoconstituents present in C. vulgare, and systematically details its diverse pharmacological properties. Additionally, the review delves into considerations of toxicity. By synthesizing this wealth of information, this study opens avenues for the potential therapeutic applications of C. vulgare. The practical value of this research lies in its contribution to the understanding of medicinal plants, mainly focusing on the pharmacological potential of C. vulgare. This exploration enriches our knowledge of traditional medicine and paves the way for innovative therapeutic approaches, offering promising prospects for future drug development. As the demand for natural remedies continues to increase, this work provides a valuable resource for researchers, practitioners, and stakeholders in herbal medicine and pharmacology.
AB - Folk medicine, rooted in historical practice, has long been used for medicinal purposes, emphasizing the need to ensure the safety, quality, and efficacy of herbal medicines. This imperative has grown over time, prompting collaborative efforts to document historical records and preserve invaluable knowledge of medicinal plants. The Lamiaceae (Labiatae) family, renowned for its rich assortment of medicinal plants characterized by high concentrations of volatile oils, stands out in this regard. This review focuses on Clinopodium vulgare (C. vulgare) L., commonly known as wild basil or basil thyme, a significant species within the Lamiaceae family found across diverse global regions. C. vulgare boasts a storied history of application in treating various ailments, such as gastric ulcers, diabetes, and inflammation, dating back to ancient times. Rigorous research has substantiated its pharmacological properties, revealing its antioxidant, antiviral, antibacterial, anti-inflammatory, anticancer, antihypertensive, and enzyme-inhibitory effects. This comprehensive review provides an insightful overview of the Lamiaceae family, elucidates the extraction methods employed to obtain medicinal compounds, explores the phytoconstituents present in C. vulgare, and systematically details its diverse pharmacological properties. Additionally, the review delves into considerations of toxicity. By synthesizing this wealth of information, this study opens avenues for the potential therapeutic applications of C. vulgare. The practical value of this research lies in its contribution to the understanding of medicinal plants, mainly focusing on the pharmacological potential of C. vulgare. This exploration enriches our knowledge of traditional medicine and paves the way for innovative therapeutic approaches, offering promising prospects for future drug development. As the demand for natural remedies continues to increase, this work provides a valuable resource for researchers, practitioners, and stakeholders in herbal medicine and pharmacology.
KW - Anti-inflammatory
KW - Anticancer
KW - Antihypertensive
KW - Antimicrobial
KW - Antioxidant
KW - Antiviral
KW - Clinopodium vulgare
KW - Phytocompounds
UR - http://www.scopus.com/inward/record.url?scp=85183028337&partnerID=8YFLogxK
U2 - 10.1016/j.heliyon.2024.e24781
DO - 10.1016/j.heliyon.2024.e24781
M3 - Review article
C2 - 38312627
AN - SCOPUS:85183028337
SN - 2405-8440
VL - 10
JO - Heliyon
JF - Heliyon
IS - 2
M1 - e24781
ER -