Abstract
The activities of a group devoted to organic synthesis in the field of polymer and oligomer chemistry have led to new types of dendritic cross-linking compounds for the polymerization of styrene to give high-quality materials. In addition the synthesis of uniform ('monodisperse'), high-molecular weight oligomers of 3-hydroxybutanoic acid provided samples for investigations to prove the hypothesis that polyhydroxybutyrates are natural ion-channel components in living organisms. Oligomers of β-amino acids were prepared and have been shown to form all the secondary structures known from natural peptides and proteins (composed of α-amino acids), i.e. helices, pleated sheets, turns, hair pins and stacks with properties differing fundamentally from those of the natural analogs.
Original language | English (US) |
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Pages (from-to) | 98-103 |
Number of pages | 6 |
Journal | Chimia |
Volume | 55 |
Issue number | 3 |
State | Published - 2001 |
Externally published | Yes |
Keywords
- Dendritic cross-linkers
- Oligo-(3-hydroxybutanoates)
- Polymer-bound chiral ligands
- Secondary structures
- β-peptides
ASJC Scopus subject areas
- General Chemistry