Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents

Ken Ichi Ohba; Masashi Mizokami; Johnson Y.N. Lau; Etsuro Orito; Kazuho Ikeo; Takashi Gojobori

doi:10.1016/0014-5793(95)01441-1

Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents

Ken Ichi Ohba, Masashi Mizokami^*, Johnson Y.N. Lau, Etsuro Orito, Kazuho Ikeo, Takashi Gojobori

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

87 Scopus citations

Abstract

Two flavivirus-like viruses, GB virus-A (GBV-A) and GB virus-B (GBV-B), were recently identified in the GB hepatitis agent, and are distinct from the hepatitis A to E viruses. The putative helicase domain of GBV-A and GBV-B was found to have amino acid sequence homology with hepatitis C virus (HCV), and distantly, is also related to pestiviruses, flaviviruses, and plant viruses. A phylogenetic tree construction showed that GBVs and HCV are closely related, and they are clustered with pestiviruses, flaviviruses and plant viruses in that order.

Original language	English (US)
Pages (from-to)	232-234
Number of pages	3
Journal	FEBS Letters
Volume	378
Issue number	3
DOIs	https://doi.org/10.1016/0014-5793(95)01441-1
State	Published - Jan 15 1996
Externally published	Yes

Keywords

Evolution
GB virus
HCV
Phylogenetic tree

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0014-5793(95)01441-1

Cite this

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title = "Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents",

abstract = "Two flavivirus-like viruses, GB virus-A (GBV-A) and GB virus-B (GBV-B), were recently identified in the GB hepatitis agent, and are distinct from the hepatitis A to E viruses. The putative helicase domain of GBV-A and GBV-B was found to have amino acid sequence homology with hepatitis C virus (HCV), and distantly, is also related to pestiviruses, flaviviruses, and plant viruses. A phylogenetic tree construction showed that GBVs and HCV are closely related, and they are clustered with pestiviruses, flaviviruses and plant viruses in that order.",

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pages = "232--234",

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T1 - Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents

AU - Ohba, Ken Ichi

AU - Mizokami, Masashi

AU - Lau, Johnson Y.N.

AU - Orito, Etsuro

AU - Ikeo, Kazuho

AU - Gojobori, Takashi

PY - 1996/1/15

Y1 - 1996/1/15

N2 - Two flavivirus-like viruses, GB virus-A (GBV-A) and GB virus-B (GBV-B), were recently identified in the GB hepatitis agent, and are distinct from the hepatitis A to E viruses. The putative helicase domain of GBV-A and GBV-B was found to have amino acid sequence homology with hepatitis C virus (HCV), and distantly, is also related to pestiviruses, flaviviruses, and plant viruses. A phylogenetic tree construction showed that GBVs and HCV are closely related, and they are clustered with pestiviruses, flaviviruses and plant viruses in that order.

AB - Two flavivirus-like viruses, GB virus-A (GBV-A) and GB virus-B (GBV-B), were recently identified in the GB hepatitis agent, and are distinct from the hepatitis A to E viruses. The putative helicase domain of GBV-A and GBV-B was found to have amino acid sequence homology with hepatitis C virus (HCV), and distantly, is also related to pestiviruses, flaviviruses, and plant viruses. A phylogenetic tree construction showed that GBVs and HCV are closely related, and they are clustered with pestiviruses, flaviviruses and plant viruses in that order.

KW - Evolution

KW - GB virus

KW - HCV

KW - Phylogenetic tree

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SP - 232

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JO - FEBS Letters

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ER -

Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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