TY - GEN
T1 - Evaluation of microfluidic channels with optical coherence tomography
AU - Czajkowski, J.
AU - Prykäri, T.
AU - Alarousu, Erkki
AU - Lauri, J.
AU - Myllylä, R.
N1 - KAUST Repository Item: Exported on 2020-10-01
PY - 2010/6/25
Y1 - 2010/6/25
N2 - Application of time domain, ultra high resolution optical coherence tomography (UHR-OCT) in evaluation of microfluidic channels is demonstrated. Presented study was done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti:sapphire femtosecond laser, a photonic crystal fibre and modified, free-space Michelson interferometer. To show potential of the technique, microfluidic chip fabricated by VTT Center for Printed Intelligence (Oulu, Finland) was measured. Ability for full volumetric reconstruction in non-contact manner enabled complete characterization of closed entity of a microfluidic channel without contamination and harm for the sample. Measurement, occurring problems, and methods of postprocessing for raw data are described. Results present completely resolved physical structure of the channel, its spatial dimensions, draft angles and evaluation of lamination quality.
AB - Application of time domain, ultra high resolution optical coherence tomography (UHR-OCT) in evaluation of microfluidic channels is demonstrated. Presented study was done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti:sapphire femtosecond laser, a photonic crystal fibre and modified, free-space Michelson interferometer. To show potential of the technique, microfluidic chip fabricated by VTT Center for Printed Intelligence (Oulu, Finland) was measured. Ability for full volumetric reconstruction in non-contact manner enabled complete characterization of closed entity of a microfluidic channel without contamination and harm for the sample. Measurement, occurring problems, and methods of postprocessing for raw data are described. Results present completely resolved physical structure of the channel, its spatial dimensions, draft angles and evaluation of lamination quality.
UR - http://hdl.handle.net/10754/555707
UR - http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=782030
UR - http://www.scopus.com/inward/record.url?scp=79953096740&partnerID=8YFLogxK
U2 - 10.1117/12.871445
DO - 10.1117/12.871445
M3 - Conference contribution
SN - 9780819476524
BT - Laser Applications in Life Sciences
PB - SPIE-Intl Soc Optical Eng
ER -