Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019

Katrin Burkart; Aaron J. Cohen; Sarah S. Wozniak; Xiaochen Dai; Lalit Dandona; Rakhi Dandona; Simon Hay; Ali H. Mokdad; Stephen S. Lim; Jeffrey D. Stanaway; Michael Brauer; Samath Dhamminda Dharmaratne; Shane Douglas Morrison; Kate Causey; Devashri Digvijay Salvi; Cristiana Abbafati; Victor Adekanmbi; Jose C. Adsuar; Keivan Ahmadi; Azeem Majeed; Fares Alahdab; Ziyad Al-Aly; Vahid Alipour; Jalal Arabloo; Aziz Rezapour; Ebrahim Babaee; Arash Tehrani-Banihashemi; Amir Kasaeian; Fatemeh Pashazadeh Kan; Nelson Alvis-Guzman; Adeladza Kofi Amegah; Catalina Liliana Andrei; Ruxandra Irina Negoi; Tudorel Andrei; Andreea Mirica; Fereshteh Ansari; Olatunde Aremu; Timur Aripov; Maciej Banach; Anthony Barnett; Ester Cerin; Till Winfried Barnighausen; Aziz Sheikh; Neeraj Bedi; Masoud Behzadifar; Yannick Bejot; Derrick A. Bennett; Sonia Lewycka; Isabela M. Bensenor; Robert S. Bernstein; Krittika Bhattacharyya; Ali Bijani; Antonio Biondi; Marco Vacante; Somayeh Bohlouli; Susanne Breitner; Hermann Brenner; Zahid A. Butt; Luis Alberto Camera; Pascual R. Valdez; Carlos Cantu-Brito; Felix Carvalho; Eduarda Fernandes; Marisa Freitas; Daniela Ribeiro; Vijay Kumar Chattu; Bal Govind Chauhan; Junaid Khan; Jee-Young Jasmine Choi; Dinh-Toi Chu; Sanjay Zodpey; Ahmad Daryani; Alireza Rafiei; Kairat Davletov; Barbora de Courten; Sojib Bin Zaman; Yuming Guo; Shanshan Li; Feleke Mekonnen Demeke; Edgar Denova-Gutierrez; Meghnath Dhimal; Daniel Diaz; Shirin Djalalinia; Bruce B. Duncan; Maria Ines Schmidt; Maysaa El Sayed Zaki; Sharareh Eskandarieh; Mohammad Ali Sahraian; Farshad Farzadfar; Bahram Mohajer; Sahar Saeedi Moghaddam; Mehdi Fazlzadeh; Afshin Maleki; Reza Malekzadeh; Hamideh Salimzadeh; Sadaf G. Sepanlou; Fakher Rahim; Vafa Rahimi-Movaghar; Reza Shirkoohi; Mohammad Fareed; Nazir Fattahi; Meghdad Pirsaheb; Ehsan Sadeghi; Kiomars Sharafi; Irina Filip; Florian Fischer; Nataliya A. Foigt; Ahmad Ghashghaee; Paramjit Singh Gill; Ibrahim Abdelmageed Ginawi; Sameer Vali Gopalani; Rajat Das Gupta; Tesfa Dejenie Habtewold; Randah R. Hamadeh; Samer Hamidi; Graeme J. Hankey; Edris Hasanpoor; Hadi Pourjafar; Hamid Yimam Hassen; Behzad Heibati; Michael K. Hole; Naznin Hossain; Mowafa Househ; Seyed Sina Naghibi Irvani; Jalil Jaafari; Mihajlo Jakovljevic; Ravi Prakash Jha; Jost B. Jonas; Jacek Jerzy Jozwiak; Neda Kaydi; Morteza Abdullatif Khafaie; Yousef Saleh Khader; Ejaz Ahmad Khan; Md Nuruzzaman Khan; Khaled Khatab; Amir M. Khater; Yun Jin Kim; Ruth W. Kimokoti; Adnan Kisa; Mika Kivimaki; Luke D. Knibbs; Soewarta Kosen; Parvaiz A. Koul; Ai Koyanagi; Barthelemy Kuate Defo; Nuworza Kugbey; Paolo Lauriola; Paul H. Lee; Mostafa Leili; Lee-Ling Lim; Shai Linn; Kerem Shuval; Yong Liu; Stefan Lorkowski; Phetole Walter Mahasha; Duduzile Edith Ndwandwe; Narayan B. Mahotra; Abdullah A. Mamun; Navid Manafi; Santi Martini; Birhanu Geta Meharie; Yonatal Mesfin Tefera; Ritesh G. Menezes; Tomislav Mestrovic; Bartosz Miazgowski; Tomasz Miazgowski; Ted R. Miller; Gk Mini; Erkin M. Mirrakhimov; Shafiu Mohammed; Viswanathan Mohan; Lorenzo Monasta; Luca Ronfani; Paula Moraga; Ulrich Otto Mueller; Satinath Mukhopadhyay; Ghulam Mustafa; Saravanan Muthupandian; Gurudatta Naik; Vinay Nangia; Dina Nur Anggraini Ningrum; Jean Jacques Noubiap; Felix Akpojene Ogbo; Andrew T. Olagunju; Thirunavukkarasu Sathish; Obinna E. Onwujekwe; Alberto Ortiz; Mayowa O. Owolabi; M. P. A. Dnb; Songhomitra Panda-Jonas; Eun-Kee Park; Maarten J. Postma; Amir Radfar; Muhammad Aziz Rahman; Rajesh Kumar Rai; Chhabi Lal Ranabhat; Samira Raoofi; Lal Rawal; Andre M. N. Renzaho; Leonardo Roever; Siamak Sabour; Basema Saddik; Amirhossein Sahebkar; Sundeep Santosh Salvi; Abdallah M. Samy; Juan Sanabria; Rodrigo Sarmiento-Suarez; Aletta Elisabeth Schutte; Masood Ali Shaikh; Mika Shigematsu; Rahman Shiri; Ireneous N. Soyiri; Rafael Tabares-Seisdedos; Mohamad-Hani Temsah; Kavumpurathu Raman Thankappan; Roman Topor-Madry; Lorainne Tudor Car; Irfan Ullah; Tommi Juhani Vasankari; Francesco S. Violante; Yasir Waheed; Charles D. A. Wolfe; Tomohide Yamada; Naohiro Yonemoto; Chuanhua Yu; Yunquan Zhang; Sanjay Zodpey; Stephen S Lim; Jeffrey D Stanaway; Michael Brauer

doi:10.1016/S2542-5196(22)00122-X

Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019

Katrin Burkart, Aaron J. Cohen, Sarah S. Wozniak, Xiaochen Dai, Lalit Dandona, Rakhi Dandona, Simon Hay, Ali H. Mokdad, Stephen S. Lim, Jeffrey D. Stanaway, Michael Brauer, Samath Dhamminda Dharmaratne, Shane Douglas Morrison, Kate Causey, Devashri Digvijay Salvi, Cristiana Abbafati, Victor Adekanmbi, Jose C. Adsuar, Keivan Ahmadi, Azeem MajeedFares Alahdab, Ziyad Al-Aly, Vahid Alipour, Jalal Arabloo, Aziz Rezapour, Ebrahim Babaee, Arash Tehrani-Banihashemi, Amir Kasaeian, Fatemeh Pashazadeh Kan, Nelson Alvis-Guzman, Adeladza Kofi Amegah, Catalina Liliana Andrei, Ruxandra Irina Negoi, Tudorel Andrei, Andreea Mirica, Fereshteh Ansari, Olatunde Aremu, Timur Aripov, Maciej Banach, Anthony Barnett, Ester Cerin, Till Winfried Barnighausen, Aziz Sheikh, Neeraj Bedi, Masoud Behzadifar, Yannick Bejot, Derrick A. Bennett, Sonia Lewycka, Isabela M. Bensenor, Robert S. Bernstein, Krittika Bhattacharyya, Ali Bijani, Antonio Biondi, Marco Vacante, Somayeh Bohlouli, Susanne Breitner, Hermann Brenner, Zahid A. Butt, Luis Alberto Camera, Pascual R. Valdez, Carlos Cantu-Brito, Felix Carvalho, Eduarda Fernandes, Marisa Freitas, Daniela Ribeiro, Vijay Kumar Chattu, Bal Govind Chauhan, Junaid Khan, Jee-Young Jasmine Choi, Dinh-Toi Chu, Sanjay Zodpey, Ahmad Daryani, Alireza Rafiei, Kairat Davletov, Barbora de Courten, Sojib Bin Zaman, Yuming Guo, Shanshan Li, Feleke Mekonnen Demeke, Edgar Denova-Gutierrez, Meghnath Dhimal, Daniel Diaz, Shirin Djalalinia, Bruce B. Duncan, Maria Ines Schmidt, Maysaa El Sayed Zaki, Sharareh Eskandarieh, Mohammad Ali Sahraian, Farshad Farzadfar, Bahram Mohajer, Sahar Saeedi Moghaddam, Mehdi Fazlzadeh, Afshin Maleki, Reza Malekzadeh, Hamideh Salimzadeh, Sadaf G. Sepanlou, Fakher Rahim, Vafa Rahimi-Movaghar, Reza Shirkoohi, Mohammad Fareed, Nazir Fattahi, Meghdad Pirsaheb, Ehsan Sadeghi, Kiomars Sharafi, Irina Filip, Florian Fischer, Nataliya A. Foigt, Ahmad Ghashghaee, Paramjit Singh Gill, Ibrahim Abdelmageed Ginawi, Sameer Vali Gopalani, Rajat Das Gupta, Tesfa Dejenie Habtewold, Randah R. Hamadeh, Samer Hamidi, Graeme J. Hankey, Edris Hasanpoor, Hadi Pourjafar, Hamid Yimam Hassen, Behzad Heibati, Michael K. Hole, Naznin Hossain, Mowafa Househ, Seyed Sina Naghibi Irvani, Jalil Jaafari, Mihajlo Jakovljevic, Ravi Prakash Jha, Jost B. Jonas, Jacek Jerzy Jozwiak, Neda Kaydi, Morteza Abdullatif Khafaie, Yousef Saleh Khader, Ejaz Ahmad Khan, Md Nuruzzaman Khan, Khaled Khatab, Amir M. Khater, Yun Jin Kim, Ruth W. Kimokoti, Adnan Kisa, Mika Kivimaki, Luke D. Knibbs, Soewarta Kosen, Parvaiz A. Koul, Ai Koyanagi, Barthelemy Kuate Defo, Nuworza Kugbey, Paolo Lauriola, Paul H. Lee, Mostafa Leili, Lee-Ling Lim, Shai Linn, Kerem Shuval, Yong Liu, Stefan Lorkowski, Phetole Walter Mahasha, Duduzile Edith Ndwandwe, Narayan B. Mahotra, Abdullah A. Mamun, Navid Manafi, Santi Martini, Birhanu Geta Meharie, Yonatal Mesfin Tefera, Ritesh G. Menezes, Tomislav Mestrovic, Bartosz Miazgowski, Tomasz Miazgowski, Ted R. Miller, Gk Mini, Erkin M. Mirrakhimov, Shafiu Mohammed, Viswanathan Mohan, Lorenzo Monasta, Luca Ronfani, Paula Moraga, Ulrich Otto Mueller, Satinath Mukhopadhyay, Ghulam Mustafa, Saravanan Muthupandian, Gurudatta Naik, Vinay Nangia, Dina Nur Anggraini Ningrum, Jean Jacques Noubiap, Felix Akpojene Ogbo, Andrew T. Olagunju, Thirunavukkarasu Sathish, Obinna E. Onwujekwe, Alberto Ortiz, Mayowa O. Owolabi, M. P. A. Dnb, Songhomitra Panda-Jonas, Eun-Kee Park, Maarten J. Postma, Amir Radfar, Muhammad Aziz Rahman, Rajesh Kumar Rai, Chhabi Lal Ranabhat, Samira Raoofi, Lal Rawal, Andre M. N. Renzaho, Leonardo Roever, Siamak Sabour, Basema Saddik, Amirhossein Sahebkar, Sundeep Santosh Salvi, Abdallah M. Samy, Juan Sanabria, Rodrigo Sarmiento-Suarez, Aletta Elisabeth Schutte, Masood Ali Shaikh, Mika Shigematsu, Rahman Shiri, Ireneous N. Soyiri, Rafael Tabares-Seisdedos, Mohamad-Hani Temsah, Kavumpurathu Raman Thankappan, Roman Topor-Madry, Lorainne Tudor Car, Irfan Ullah, Tommi Juhani Vasankari, Francesco S. Violante, Yasir Waheed, Charles D. A. Wolfe, Tomohide Yamada, Naohiro Yonemoto, Chuanhua Yu, Yunquan Zhang, Sanjay Zodpey, Stephen S Lim, Jeffrey D Stanaway, Michael Brauer

Research output: Contribution to journal › Article › peer-review

113 Scopus citations

Abstract

Background Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2.5 originating from ambient and household air pollution. Methods We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2.5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure-response curve from the extracted relative risk estimates using the MR-BRT (meta-regression-Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM2.5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM2.5-attributable type 2 diabetes burden. All estimates are presented with 95% uncertainty intervals. Findings In 2019, approximately a fifth of the global burden of type 2 diabetes was attributable to PM2.5 exposure, with an estimated 3.78 (95% uncertainty interval 2.68-4.83) deaths per 100 000 population and 167 (117-223) disability-adjusted life-years (DALYs) per 100 000 population. Approximately 13.4% (9.49-17.5) of deaths and 13.6% (9.73-17.9) of DALYs due to type 2 diabetes were contributed by ambient PM2.5, and 6.50% (4.22-9.53) of deaths and 5.92% (3.81-8.64) of DALYs by household air pollution. High burdens, in terms of numbers as well as rates, were estimated in Asia, sub-Saharan Africa, and South America. Since 1990, the attributable burden has increased by 50%, driven largely by population growth and ageing. Globally, the impact of reductions in household air pollution was largely offset by increased ambient PM2.5. Interpretation Air pollution is a major risk factor for diabetes. We estimated that about a fifth of the global burden of type 2 diabetes is attributable PM2.5 pollution. Air pollution mitigation therefore might have an essential role in reducing the global disease burden resulting from type 2 diabetes. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.

Original language	English (US)
Pages (from-to)	E586-E600
Journal	LANCET PLANETARY HEALTH
Volume	6
Issue number	7
DOIs	https://doi.org/10.1016/S2542-5196(22)00122-X
State	Published - Jul 6 2022

Bibliographical note

KAUST Repository Item: Exported on 2022-11-30
Acknowledgements: This study is funded by the Bill & Melinda Gates Foundation.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/S2542-5196(22)00122-X

https://repository.kaust.edu.sa/bitstream/10754/686000/1/PIIS254251962200122X.pdf

Cite this

Burkart, K., Cohen, A. J., Wozniak, S. S., Dai, X., Dandona, L., Dandona, R., Hay, S., Mokdad, A. H., Lim, S. S., Stanaway, J. D., Brauer, M., Dharmaratne, S. D., Morrison, S. D., Causey, K., Salvi, D. D., Abbafati, C., Adekanmbi, V., Adsuar, J. C., Ahmadi, K., ... Brauer, M. (2022). Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019. LANCET PLANETARY HEALTH, 6(7), E586-E600. https://doi.org/10.1016/S2542-5196(22)00122-X

@article{ccca5d1d06874ec1bb38e27bbed328dc,

title = "Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019",

abstract = "Background Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2.5 originating from ambient and household air pollution. Methods We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2.5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure-response curve from the extracted relative risk estimates using the MR-BRT (meta-regression-Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM2.5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM2.5-attributable type 2 diabetes burden. All estimates are presented with 95% uncertainty intervals. Findings In 2019, approximately a fifth of the global burden of type 2 diabetes was attributable to PM2.5 exposure, with an estimated 3.78 (95% uncertainty interval 2.68-4.83) deaths per 100 000 population and 167 (117-223) disability-adjusted life-years (DALYs) per 100 000 population. Approximately 13.4% (9.49-17.5) of deaths and 13.6% (9.73-17.9) of DALYs due to type 2 diabetes were contributed by ambient PM2.5, and 6.50% (4.22-9.53) of deaths and 5.92% (3.81-8.64) of DALYs by household air pollution. High burdens, in terms of numbers as well as rates, were estimated in Asia, sub-Saharan Africa, and South America. Since 1990, the attributable burden has increased by 50%, driven largely by population growth and ageing. Globally, the impact of reductions in household air pollution was largely offset by increased ambient PM2.5. Interpretation Air pollution is a major risk factor for diabetes. We estimated that about a fifth of the global burden of type 2 diabetes is attributable PM2.5 pollution. Air pollution mitigation therefore might have an essential role in reducing the global disease burden resulting from type 2 diabetes. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.",

author = "Katrin Burkart and Cohen, {Aaron J.} and Wozniak, {Sarah S.} and Xiaochen Dai and Lalit Dandona and Rakhi Dandona and Simon Hay and Mokdad, {Ali H.} and Lim, {Stephen S.} and Stanaway, {Jeffrey D.} and Michael Brauer and Dharmaratne, {Samath Dhamminda} and Morrison, {Shane Douglas} and Kate Causey and Salvi, {Devashri Digvijay} and Cristiana Abbafati and Victor Adekanmbi and Adsuar, {Jose C.} and Keivan Ahmadi and Azeem Majeed and Fares Alahdab and Ziyad Al-Aly and Vahid Alipour and Jalal Arabloo and Aziz Rezapour and Ebrahim Babaee and Arash Tehrani-Banihashemi and Amir Kasaeian and Kan, {Fatemeh Pashazadeh} and Nelson Alvis-Guzman and Amegah, {Adeladza Kofi} and Andrei, {Catalina Liliana} and Negoi, {Ruxandra Irina} and Tudorel Andrei and Andreea Mirica and Fereshteh Ansari and Olatunde Aremu and Timur Aripov and Maciej Banach and Anthony Barnett and Ester Cerin and Barnighausen, {Till Winfried} and Aziz Sheikh and Neeraj Bedi and Masoud Behzadifar and Yannick Bejot and Bennett, {Derrick A.} and Sonia Lewycka and Bensenor, {Isabela M.} and Bernstein, {Robert S.} and Krittika Bhattacharyya and Ali Bijani and Antonio Biondi and Marco Vacante and Somayeh Bohlouli and Susanne Breitner and Hermann Brenner and Butt, {Zahid A.} and Camera, {Luis Alberto} and Valdez, {Pascual R.} and Carlos Cantu-Brito and Felix Carvalho and Eduarda Fernandes and Marisa Freitas and Daniela Ribeiro and Chattu, {Vijay Kumar} and Chauhan, {Bal Govind} and Junaid Khan and Choi, {Jee-Young Jasmine} and Dinh-Toi Chu and Sanjay Zodpey and Ahmad Daryani and Alireza Rafiei and Kairat Davletov and {de Courten}, Barbora and {Bin Zaman}, Sojib and Yuming Guo and Shanshan Li and Demeke, {Feleke Mekonnen} and Edgar Denova-Gutierrez and Meghnath Dhimal and Daniel Diaz and Shirin Djalalinia and Duncan, {Bruce B.} and Schmidt, {Maria Ines} and Zaki, {Maysaa El Sayed} and Sharareh Eskandarieh and Sahraian, {Mohammad Ali} and Farshad Farzadfar and Bahram Mohajer and Moghaddam, {Sahar Saeedi} and Mehdi Fazlzadeh and Afshin Maleki and Reza Malekzadeh and Hamideh Salimzadeh and Sepanlou, {Sadaf G.} and Fakher Rahim and Vafa Rahimi-Movaghar and Reza Shirkoohi and Mohammad Fareed and Nazir Fattahi and Meghdad Pirsaheb and Ehsan Sadeghi and Kiomars Sharafi and Irina Filip and Florian Fischer and Foigt, {Nataliya A.} and Ahmad Ghashghaee and Gill, {Paramjit Singh} and Ginawi, {Ibrahim Abdelmageed} and Gopalani, {Sameer Vali} and {Das Gupta}, Rajat and Habtewold, {Tesfa Dejenie} and Hamadeh, {Randah R.} and Samer Hamidi and Hankey, {Graeme J.} and Edris Hasanpoor and Hadi Pourjafar and Hassen, {Hamid Yimam} and Behzad Heibati and Hole, {Michael K.} and Naznin Hossain and Mowafa Househ and Irvani, {Seyed Sina Naghibi} and Jalil Jaafari and Mihajlo Jakovljevic and Jha, {Ravi Prakash} and Jonas, {Jost B.} and Jozwiak, {Jacek Jerzy} and Neda Kaydi and Khafaie, {Morteza Abdullatif} and Khader, {Yousef Saleh} and Khan, {Ejaz Ahmad} and Khan, {Md Nuruzzaman} and Khaled Khatab and Khater, {Amir M.} and Kim, {Yun Jin} and Kimokoti, {Ruth W.} and Adnan Kisa and Mika Kivimaki and Knibbs, {Luke D.} and Soewarta Kosen and Koul, {Parvaiz A.} and Ai Koyanagi and Defo, {Barthelemy Kuate} and Nuworza Kugbey and Paolo Lauriola and Lee, {Paul H.} and Mostafa Leili and Lee-Ling Lim and Shai Linn and Kerem Shuval and Yong Liu and Stefan Lorkowski and Mahasha, {Phetole Walter} and Ndwandwe, {Duduzile Edith} and Mahotra, {Narayan B.} and Mamun, {Abdullah A.} and Navid Manafi and Santi Martini and Meharie, {Birhanu Geta} and Tefera, {Yonatal Mesfin} and Menezes, {Ritesh G.} and Tomislav Mestrovic and Bartosz Miazgowski and Tomasz Miazgowski and Miller, {Ted R.} and Gk Mini and Mirrakhimov, {Erkin M.} and Shafiu Mohammed and Viswanathan Mohan and Lorenzo Monasta and Luca Ronfani and Paula Moraga and Mueller, {Ulrich Otto} and Satinath Mukhopadhyay and Ghulam Mustafa and Saravanan Muthupandian and Gurudatta Naik and Vinay Nangia and Ningrum, {Dina Nur Anggraini} and Noubiap, {Jean Jacques} and Ogbo, {Felix Akpojene} and Olagunju, {Andrew T.} and Thirunavukkarasu Sathish and Onwujekwe, {Obinna E.} and Alberto Ortiz and Owolabi, {Mayowa O.} and Dnb, {M. P. A.} and Songhomitra Panda-Jonas and Eun-Kee Park and Postma, {Maarten J.} and Amir Radfar and Rahman, {Muhammad Aziz} and Rai, {Rajesh Kumar} and Ranabhat, {Chhabi Lal} and Samira Raoofi and Lal Rawal and Renzaho, {Andre M. N.} and Leonardo Roever and Siamak Sabour and Basema Saddik and Amirhossein Sahebkar and Salvi, {Sundeep Santosh} and Samy, {Abdallah M.} and Juan Sanabria and Rodrigo Sarmiento-Suarez and Schutte, {Aletta Elisabeth} and Shaikh, {Masood Ali} and Mika Shigematsu and Rahman Shiri and Soyiri, {Ireneous N.} and Rafael Tabares-Seisdedos and Mohamad-Hani Temsah and Thankappan, {Kavumpurathu Raman} and Roman Topor-Madry and Car, {Lorainne Tudor} and Irfan Ullah and Vasankari, {Tommi Juhani} and Violante, {Francesco S.} and Yasir Waheed and Wolfe, {Charles D. A.} and Tomohide Yamada and Naohiro Yonemoto and Chuanhua Yu and Yunquan Zhang and Sanjay Zodpey and Lim, {Stephen S} and Stanaway, {Jeffrey D} and Michael Brauer",

note = "KAUST Repository Item: Exported on 2022-11-30 Acknowledgements: This study is funded by the Bill & Melinda Gates Foundation.",

year = "2022",

month = jul,

day = "6",

doi = "10.1016/S2542-5196(22)00122-X",

language = "English (US)",

volume = "6",

pages = "E586--E600",

journal = "LANCET PLANETARY HEALTH",

issn = "2542-5196",

publisher = "Elsevier",

number = "7",

}

Burkart, K, Cohen, AJ, Wozniak, SS, Dai, X, Dandona, L, Dandona, R, Hay, S, Mokdad, AH, Lim, SS, Stanaway, JD, Brauer, M, Dharmaratne, SD, Morrison, SD, Causey, K, Salvi, DD, Abbafati, C, Adekanmbi, V, Adsuar, JC, Ahmadi, K, Majeed, A, Alahdab, F, Al-Aly, Z, Alipour, V, Arabloo, J, Rezapour, A, Babaee, E, Tehrani-Banihashemi, A, Kasaeian, A, Kan, FP, Alvis-Guzman, N, Amegah, AK, Andrei, CL, Negoi, RI, Andrei, T, Mirica, A, Ansari, F, Aremu, O, Aripov, T, Banach, M, Barnett, A, Cerin, E, Barnighausen, TW, Sheikh, A, Bedi, N, Behzadifar, M, Bejot, Y, Bennett, DA, Lewycka, S, Bensenor, IM, Bernstein, RS, Bhattacharyya, K, Bijani, A, Biondi, A, Vacante, M, Bohlouli, S, Breitner, S, Brenner, H, Butt, ZA, Camera, LA, Valdez, PR, Cantu-Brito, C, Carvalho, F, Fernandes, E, Freitas, M, Ribeiro, D, Chattu, VK, Chauhan, BG, Khan, J, Choi, J-YJ, Chu, D-T, Zodpey, S, Daryani, A, Rafiei, A, Davletov, K, de Courten, B, Bin Zaman, S, Guo, Y, Li, S, Demeke, FM, Denova-Gutierrez, E, Dhimal, M, Diaz, D, Djalalinia, S, Duncan, BB, Schmidt, MI, Zaki, MES, Eskandarieh, S, Sahraian, MA, Farzadfar, F, Mohajer, B, Moghaddam, SS, Fazlzadeh, M, Maleki, A, Malekzadeh, R, Salimzadeh, H, Sepanlou, SG, Rahim, F, Rahimi-Movaghar, V, Shirkoohi, R, Fareed, M, Fattahi, N, Pirsaheb, M, Sadeghi, E, Sharafi, K, Filip, I, Fischer, F, Foigt, NA, Ghashghaee, A, Gill, PS, Ginawi, IA, Gopalani, SV, Das Gupta, R, Habtewold, TD, Hamadeh, RR, Hamidi, S, Hankey, GJ, Hasanpoor, E, Pourjafar, H, Hassen, HY, Heibati, B, Hole, MK, Hossain, N, Househ, M, Irvani, SSN, Jaafari, J, Jakovljevic, M, Jha, RP, Jonas, JB, Jozwiak, JJ, Kaydi, N, Khafaie, MA, Khader, YS, Khan, EA, Khan, MN, Khatab, K, Khater, AM, Kim, YJ, Kimokoti, RW, Kisa, A, Kivimaki, M, Knibbs, LD, Kosen, S, Koul, PA, Koyanagi, A, Defo, BK, Kugbey, N, Lauriola, P, Lee, PH, Leili, M, Lim, L-L, Linn, S, Shuval, K, Liu, Y, Lorkowski, S, Mahasha, PW, Ndwandwe, DE, Mahotra, NB, Mamun, AA, Manafi, N, Martini, S, Meharie, BG, Tefera, YM, Menezes, RG, Mestrovic, T, Miazgowski, B, Miazgowski, T, Miller, TR, Mini, G, Mirrakhimov, EM, Mohammed, S, Mohan, V, Monasta, L, Ronfani, L, Moraga, P, Mueller, UO, Mukhopadhyay, S, Mustafa, G, Muthupandian, S, Naik, G, Nangia, V, Ningrum, DNA, Noubiap, JJ, Ogbo, FA, Olagunju, AT, Sathish, T, Onwujekwe, OE, Ortiz, A, Owolabi, MO, Dnb, MPA, Panda-Jonas, S, Park, E-K, Postma, MJ, Radfar, A, Rahman, MA, Rai, RK, Ranabhat, CL, Raoofi, S, Rawal, L, Renzaho, AMN, Roever, L, Sabour, S, Saddik, B, Sahebkar, A, Salvi, SS, Samy, AM, Sanabria, J, Sarmiento-Suarez, R, Schutte, AE, Shaikh, MA, Shigematsu, M, Shiri, R, Soyiri, IN, Tabares-Seisdedos, R, Temsah, M-H, Thankappan, KR, Topor-Madry, R, Car, LT, Ullah, I, Vasankari, TJ, Violante, FS, Waheed, Y, Wolfe, CDA, Yamada, T, Yonemoto, N, Yu, C, Zhang, Y, Zodpey, S, Lim, SS, Stanaway, JD & Brauer, M 2022, 'Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019', LANCET PLANETARY HEALTH, vol. 6, no. 7, pp. E586-E600. https://doi.org/10.1016/S2542-5196(22)00122-X

Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019. / Burkart, Katrin; Cohen, Aaron J.; Wozniak, Sarah S. et al.
In: LANCET PLANETARY HEALTH, Vol. 6, No. 7, 06.07.2022, p. E586-E600.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019

AU - Burkart, Katrin

AU - Cohen, Aaron J.

AU - Wozniak, Sarah S.

AU - Dai, Xiaochen

AU - Dandona, Lalit

AU - Dandona, Rakhi

AU - Hay, Simon

AU - Mokdad, Ali H.

AU - Lim, Stephen S.

AU - Stanaway, Jeffrey D.

AU - Brauer, Michael

AU - Dharmaratne, Samath Dhamminda

AU - Morrison, Shane Douglas

AU - Causey, Kate

AU - Salvi, Devashri Digvijay

AU - Abbafati, Cristiana

AU - Adekanmbi, Victor

AU - Adsuar, Jose C.

AU - Ahmadi, Keivan

AU - Majeed, Azeem

AU - Alahdab, Fares

AU - Al-Aly, Ziyad

AU - Alipour, Vahid

AU - Arabloo, Jalal

AU - Rezapour, Aziz

AU - Babaee, Ebrahim

AU - Tehrani-Banihashemi, Arash

AU - Kasaeian, Amir

AU - Kan, Fatemeh Pashazadeh

AU - Alvis-Guzman, Nelson

AU - Amegah, Adeladza Kofi

AU - Andrei, Catalina Liliana

AU - Negoi, Ruxandra Irina

AU - Andrei, Tudorel

AU - Mirica, Andreea

AU - Ansari, Fereshteh

AU - Aremu, Olatunde

AU - Aripov, Timur

AU - Banach, Maciej

AU - Barnett, Anthony

AU - Cerin, Ester

AU - Barnighausen, Till Winfried

AU - Sheikh, Aziz

AU - Bedi, Neeraj

AU - Behzadifar, Masoud

AU - Bejot, Yannick

AU - Bennett, Derrick A.

AU - Lewycka, Sonia

AU - Bensenor, Isabela M.

AU - Bernstein, Robert S.

AU - Bhattacharyya, Krittika

AU - Bijani, Ali

AU - Biondi, Antonio

AU - Vacante, Marco

AU - Bohlouli, Somayeh

AU - Breitner, Susanne

AU - Brenner, Hermann

AU - Butt, Zahid A.

AU - Camera, Luis Alberto

AU - Valdez, Pascual R.

AU - Cantu-Brito, Carlos

AU - Carvalho, Felix

AU - Fernandes, Eduarda

AU - Freitas, Marisa

AU - Ribeiro, Daniela

AU - Chattu, Vijay Kumar

AU - Chauhan, Bal Govind

AU - Khan, Junaid

AU - Choi, Jee-Young Jasmine

AU - Chu, Dinh-Toi

AU - Zodpey, Sanjay

AU - Daryani, Ahmad

AU - Rafiei, Alireza

AU - Davletov, Kairat

AU - de Courten, Barbora

AU - Bin Zaman, Sojib

AU - Guo, Yuming

AU - Li, Shanshan

AU - Demeke, Feleke Mekonnen

AU - Denova-Gutierrez, Edgar

AU - Dhimal, Meghnath

AU - Diaz, Daniel

AU - Djalalinia, Shirin

AU - Duncan, Bruce B.

AU - Schmidt, Maria Ines

AU - Zaki, Maysaa El Sayed

AU - Eskandarieh, Sharareh

AU - Sahraian, Mohammad Ali

AU - Farzadfar, Farshad

AU - Mohajer, Bahram

AU - Moghaddam, Sahar Saeedi

AU - Fazlzadeh, Mehdi

AU - Maleki, Afshin

AU - Malekzadeh, Reza

AU - Salimzadeh, Hamideh

AU - Sepanlou, Sadaf G.

AU - Rahim, Fakher

AU - Rahimi-Movaghar, Vafa

AU - Shirkoohi, Reza

AU - Fareed, Mohammad

AU - Fattahi, Nazir

AU - Pirsaheb, Meghdad

AU - Sadeghi, Ehsan

AU - Sharafi, Kiomars

AU - Filip, Irina

AU - Fischer, Florian

AU - Foigt, Nataliya A.

AU - Ghashghaee, Ahmad

AU - Gill, Paramjit Singh

AU - Ginawi, Ibrahim Abdelmageed

AU - Gopalani, Sameer Vali

AU - Das Gupta, Rajat

AU - Habtewold, Tesfa Dejenie

AU - Hamadeh, Randah R.

AU - Hamidi, Samer

AU - Hankey, Graeme J.

AU - Hasanpoor, Edris

AU - Pourjafar, Hadi

AU - Hassen, Hamid Yimam

AU - Heibati, Behzad

AU - Hole, Michael K.

AU - Hossain, Naznin

AU - Househ, Mowafa

AU - Irvani, Seyed Sina Naghibi

AU - Jaafari, Jalil

AU - Jakovljevic, Mihajlo

AU - Jha, Ravi Prakash

AU - Jonas, Jost B.

AU - Jozwiak, Jacek Jerzy

AU - Kaydi, Neda

AU - Khafaie, Morteza Abdullatif

AU - Khader, Yousef Saleh

AU - Khan, Ejaz Ahmad

AU - Khan, Md Nuruzzaman

AU - Khatab, Khaled

AU - Khater, Amir M.

AU - Kim, Yun Jin

AU - Kimokoti, Ruth W.

AU - Kisa, Adnan

AU - Kivimaki, Mika

AU - Knibbs, Luke D.

AU - Kosen, Soewarta

AU - Koul, Parvaiz A.

AU - Koyanagi, Ai

AU - Defo, Barthelemy Kuate

AU - Kugbey, Nuworza

AU - Lauriola, Paolo

AU - Lee, Paul H.

AU - Leili, Mostafa

AU - Lim, Lee-Ling

AU - Linn, Shai

AU - Shuval, Kerem

AU - Liu, Yong

AU - Lorkowski, Stefan

AU - Mahasha, Phetole Walter

AU - Ndwandwe, Duduzile Edith

AU - Mahotra, Narayan B.

AU - Mamun, Abdullah A.

AU - Manafi, Navid

AU - Martini, Santi

AU - Meharie, Birhanu Geta

AU - Tefera, Yonatal Mesfin

AU - Menezes, Ritesh G.

AU - Mestrovic, Tomislav

AU - Miazgowski, Bartosz

AU - Miazgowski, Tomasz

AU - Miller, Ted R.

AU - Mini, Gk

AU - Mirrakhimov, Erkin M.

AU - Mohammed, Shafiu

AU - Mohan, Viswanathan

AU - Monasta, Lorenzo

AU - Ronfani, Luca

AU - Moraga, Paula

AU - Mueller, Ulrich Otto

AU - Mukhopadhyay, Satinath

AU - Mustafa, Ghulam

AU - Muthupandian, Saravanan

AU - Naik, Gurudatta

AU - Nangia, Vinay

AU - Ningrum, Dina Nur Anggraini

AU - Noubiap, Jean Jacques

AU - Ogbo, Felix Akpojene

AU - Olagunju, Andrew T.

AU - Sathish, Thirunavukkarasu

AU - Onwujekwe, Obinna E.

AU - Ortiz, Alberto

AU - Owolabi, Mayowa O.

AU - Dnb, M. P. A.

AU - Panda-Jonas, Songhomitra

AU - Park, Eun-Kee

AU - Postma, Maarten J.

AU - Radfar, Amir

AU - Rahman, Muhammad Aziz

AU - Rai, Rajesh Kumar

AU - Ranabhat, Chhabi Lal

AU - Raoofi, Samira

AU - Rawal, Lal

AU - Renzaho, Andre M. N.

AU - Roever, Leonardo

AU - Sabour, Siamak

AU - Saddik, Basema

AU - Sahebkar, Amirhossein

AU - Salvi, Sundeep Santosh

AU - Samy, Abdallah M.

AU - Sanabria, Juan

AU - Sarmiento-Suarez, Rodrigo

AU - Schutte, Aletta Elisabeth

AU - Shaikh, Masood Ali

AU - Shigematsu, Mika

AU - Shiri, Rahman

AU - Soyiri, Ireneous N.

AU - Tabares-Seisdedos, Rafael

AU - Temsah, Mohamad-Hani

AU - Thankappan, Kavumpurathu Raman

AU - Topor-Madry, Roman

AU - Car, Lorainne Tudor

AU - Ullah, Irfan

AU - Vasankari, Tommi Juhani

AU - Violante, Francesco S.

AU - Waheed, Yasir

AU - Wolfe, Charles D. A.

AU - Yamada, Tomohide

AU - Yonemoto, Naohiro

AU - Yu, Chuanhua

AU - Zhang, Yunquan

AU - Zodpey, Sanjay

AU - Lim, Stephen S

AU - Stanaway, Jeffrey D

AU - Brauer, Michael

N1 - KAUST Repository Item: Exported on 2022-11-30 Acknowledgements: This study is funded by the Bill & Melinda Gates Foundation.

PY - 2022/7/6

Y1 - 2022/7/6

N2 - Background Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2.5 originating from ambient and household air pollution. Methods We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2.5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure-response curve from the extracted relative risk estimates using the MR-BRT (meta-regression-Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM2.5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM2.5-attributable type 2 diabetes burden. All estimates are presented with 95% uncertainty intervals. Findings In 2019, approximately a fifth of the global burden of type 2 diabetes was attributable to PM2.5 exposure, with an estimated 3.78 (95% uncertainty interval 2.68-4.83) deaths per 100 000 population and 167 (117-223) disability-adjusted life-years (DALYs) per 100 000 population. Approximately 13.4% (9.49-17.5) of deaths and 13.6% (9.73-17.9) of DALYs due to type 2 diabetes were contributed by ambient PM2.5, and 6.50% (4.22-9.53) of deaths and 5.92% (3.81-8.64) of DALYs by household air pollution. High burdens, in terms of numbers as well as rates, were estimated in Asia, sub-Saharan Africa, and South America. Since 1990, the attributable burden has increased by 50%, driven largely by population growth and ageing. Globally, the impact of reductions in household air pollution was largely offset by increased ambient PM2.5. Interpretation Air pollution is a major risk factor for diabetes. We estimated that about a fifth of the global burden of type 2 diabetes is attributable PM2.5 pollution. Air pollution mitigation therefore might have an essential role in reducing the global disease burden resulting from type 2 diabetes. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.

AB - Background Experimental and epidemiological studies indicate an association between exposure to particulate matter (PM) air pollution and increased risk of type 2 diabetes. In view of the high and increasing prevalence of diabetes, we aimed to quantify the burden of type 2 diabetes attributable to PM2.5 originating from ambient and household air pollution. Methods We systematically compiled all relevant cohort and case-control studies assessing the effect of exposure to household and ambient fine particulate matter (PM2.5) air pollution on type 2 diabetes incidence and mortality. We derived an exposure-response curve from the extracted relative risk estimates using the MR-BRT (meta-regression-Bayesian, regularised, trimmed) tool. The estimated curve was linked to ambient and household PM2.5 exposures from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019, and estimates of the attributable burden (population attributable fractions and rates per 100 000 population of deaths and disability-adjusted life-years) for 204 countries from 1990 to 2019 were calculated. We also assessed the role of changes in exposure, population size, age, and type 2 diabetes incidence in the observed trend in PM2.5-attributable type 2 diabetes burden. All estimates are presented with 95% uncertainty intervals. Findings In 2019, approximately a fifth of the global burden of type 2 diabetes was attributable to PM2.5 exposure, with an estimated 3.78 (95% uncertainty interval 2.68-4.83) deaths per 100 000 population and 167 (117-223) disability-adjusted life-years (DALYs) per 100 000 population. Approximately 13.4% (9.49-17.5) of deaths and 13.6% (9.73-17.9) of DALYs due to type 2 diabetes were contributed by ambient PM2.5, and 6.50% (4.22-9.53) of deaths and 5.92% (3.81-8.64) of DALYs by household air pollution. High burdens, in terms of numbers as well as rates, were estimated in Asia, sub-Saharan Africa, and South America. Since 1990, the attributable burden has increased by 50%, driven largely by population growth and ageing. Globally, the impact of reductions in household air pollution was largely offset by increased ambient PM2.5. Interpretation Air pollution is a major risk factor for diabetes. We estimated that about a fifth of the global burden of type 2 diabetes is attributable PM2.5 pollution. Air pollution mitigation therefore might have an essential role in reducing the global disease burden resulting from type 2 diabetes. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd.

UR - http://hdl.handle.net/10754/686000

UR - https://linkinghub.elsevier.com/retrieve/pii/S254251962200122X

U2 - 10.1016/S2542-5196(22)00122-X

DO - 10.1016/S2542-5196(22)00122-X

M3 - Article

C2 - 35809588

SN - 2542-5196

VL - 6

SP - E586-E600

JO - LANCET PLANETARY HEALTH

JF - LANCET PLANETARY HEALTH

IS - 7

ER -

Estimates, trends, and drivers of the global burden of type 2 diabetes attributable to PM2.5 air pollution, 1990-2019: an analysis of data from the Global Burden of Disease Study 2019

Abstract

Bibliographical note

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this