Enzyme catalysis with artificial membranes towards process intensification in biorefinery- A review

Rosalinda Mazzei, Abaynesh Yihdego Gebreyohannes, Emmaouil Papaioannou, Suzana Pereira Nunes, Ivo F.J. Vankelecom, Lidietta Giorno

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


In this review, for the first time, the conjugation of the major types of enzymes used in biorefineries and the membrane processes to develop different configurations of MBRs, was analyzed for the production of biofuels, phytotherapics, food ingredients, etc. In particular, the aim is to critically review all the works related to the application of MBR in biorefinery, highlighting the advantages and the main drawbacks which can interfere with the development of this system at industrial scale. Alternatives strategies to overcome main limits will be also described in the different application fields, such as the use of biofunctionalized magnetic nanoparticles associated with membrane processes for enzyme re-use and membrane cleaning or the membrane fouling control by the use of integrated membrane process associated with MBR.
Original languageEnglish (US)
Pages (from-to)125248
JournalBioresource Technology
StatePublished - May 2021

Bibliographical note

KAUST Repository Item: Exported on 2021-05-06
Acknowledged KAUST grant number(s): REP/1/3988-06-01, REP/1/3988-09-01
Acknowledgements: The authors thank the International Exchanges 2019 Round 2 of The Royal Society, contract number IES\R2\192205 for the financial support. This work was sponsored by King Abdullah University of Science and Technology (KAUST), grants REP/1/3988-06-01 and REP/1/3988-09-01.

ASJC Scopus subject areas

  • Bioengineering
  • Environmental Engineering
  • Waste Management and Disposal


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