Dynamics of acoustic droplet vaporization in gas embolotherapy

Adnan Qamar; Zheng Z. Wong; J. Brian Fowlkes; Joseph L. Bull

doi:10.1063/1.3376763

Dynamics of acoustic droplet vaporization in gas embolotherapy

Adnan Qamar^*, Zheng Z. Wong, J. Brian Fowlkes, Joseph L. Bull

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Acoustic droplet vaporization is investigated in a theoretical model. This work is motivated by gas embolotherapy, a developmental cancer treatment involving tumor infarction with gas microbubbles that are selectively formed from liquid droplets. The results indicate that there exists a threshold value for initial droplet size below which the bubble evolution is oscillatory and above which it is smooth and asymptotic, and show that the vaporization process affects the subsequent microbubble expansion. Dampening of the bubble expansion is observed for higher viscosity and surface tension, with effects more pronounced for droplet size less than 6 μm in radius.

Original language	English (US)
Article number	143702
Journal	Applied Physics Letters
Volume	96
Issue number	14
DOIs	https://doi.org/10.1063/1.3376763
State	Published - 2010
Externally published	Yes

Bibliographical note

Funding Information:
This work was funded by NIH Grant No. R01EB006476.

ASJC Scopus subject areas

Physics and Astronomy (miscellaneous)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1063/1.3376763

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title = "Dynamics of acoustic droplet vaporization in gas embolotherapy",

abstract = "Acoustic droplet vaporization is investigated in a theoretical model. This work is motivated by gas embolotherapy, a developmental cancer treatment involving tumor infarction with gas microbubbles that are selectively formed from liquid droplets. The results indicate that there exists a threshold value for initial droplet size below which the bubble evolution is oscillatory and above which it is smooth and asymptotic, and show that the vaporization process affects the subsequent microbubble expansion. Dampening of the bubble expansion is observed for higher viscosity and surface tension, with effects more pronounced for droplet size less than 6 μm in radius.",

author = "Adnan Qamar and Wong, {Zheng Z.} and Fowlkes, {J. Brian} and Bull, {Joseph L.}",

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AU - Qamar, Adnan

AU - Wong, Zheng Z.

AU - Fowlkes, J. Brian

AU - Bull, Joseph L.

N1 - Funding Information: This work was funded by NIH Grant No. R01EB006476.

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Y1 - 2010

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AB - Acoustic droplet vaporization is investigated in a theoretical model. This work is motivated by gas embolotherapy, a developmental cancer treatment involving tumor infarction with gas microbubbles that are selectively formed from liquid droplets. The results indicate that there exists a threshold value for initial droplet size below which the bubble evolution is oscillatory and above which it is smooth and asymptotic, and show that the vaporization process affects the subsequent microbubble expansion. Dampening of the bubble expansion is observed for higher viscosity and surface tension, with effects more pronounced for droplet size less than 6 μm in radius.

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Dynamics of acoustic droplet vaporization in gas embolotherapy

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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