Dragon promoter finder: Recognition of vertebrate RNA polymerase II promoters

Vladimir B. Bajic; Seng Hong Seah; Allen Chong; Guanglan Zhang; Judice L.Y. Koh; Vladimir Brusic

doi:10.1093/bioinformatics/18.1.198

Dragon promoter finder: Recognition of vertebrate RNA polymerase II promoters

Vladimir B. Bajic^*, Seng Hong Seah, Allen Chong, Guanglan Zhang, Judice L.Y. Koh, Vladimir Brusic

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

Dragon Promoter Finder (DPF) locates RNA polymerase II promoters in DNA sequences of vertebrates by predicting Transcription Start Site (TSS) positions. DPF's algorithm uses sensors for three functional regions (promoters, exons and introns) and an Artificial Neural Network (ANN). Results on a large and diverse evaluation set indicate that DPF exhibits a superior predicting ability for TSS location compared to three other promoter-finding programs.

Original language	English (US)
Pages (from-to)	198-199
Number of pages	2
Journal	Bioinformatics
Volume	18
Issue number	1
DOIs	https://doi.org/10.1093/bioinformatics/18.1.198
State	Published - 2002
Externally published	Yes

ASJC Scopus subject areas

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

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10.1093/bioinformatics/18.1.198

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abstract = "Dragon Promoter Finder (DPF) locates RNA polymerase II promoters in DNA sequences of vertebrates by predicting Transcription Start Site (TSS) positions. DPF's algorithm uses sensors for three functional regions (promoters, exons and introns) and an Artificial Neural Network (ANN). Results on a large and diverse evaluation set indicate that DPF exhibits a superior predicting ability for TSS location compared to three other promoter-finding programs.",

author = "Bajic, {Vladimir B.} and Seah, {Seng Hong} and Allen Chong and Guanglan Zhang and Koh, {Judice L.Y.} and Vladimir Brusic",

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AU - Zhang, Guanglan

AU - Koh, Judice L.Y.

AU - Brusic, Vladimir

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AB - Dragon Promoter Finder (DPF) locates RNA polymerase II promoters in DNA sequences of vertebrates by predicting Transcription Start Site (TSS) positions. DPF's algorithm uses sensors for three functional regions (promoters, exons and introns) and an Artificial Neural Network (ANN). Results on a large and diverse evaluation set indicate that DPF exhibits a superior predicting ability for TSS location compared to three other promoter-finding programs.

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Dragon promoter finder: Recognition of vertebrate RNA polymerase II promoters

Abstract

ASJC Scopus subject areas

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