DimSUM: Dimension and Scale Unifying Map for Visual Abstraction of DNA Origami Structures

H. Miao, E. De Llano, T. Isenberg, M. E. Gröller, I. Barišić, I. Viola

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

We present a novel visualization concept for DNA origami structures that integrates a multitude of representations into a Dimension and Scale Unifying Map (DimSUM). This novel abstraction map provides means to analyze, smoothly transition between, and interact with many visual representations of the DNA origami structures in an effective way that was not possible before. DNA origami structures are nanoscale objects, which are challenging to model in silico. In our holistic approach we seamlessly combine three-dimensional realistic shape models, two-dimensional diagrammatic representations, and ordered alignments in one-dimensional arrangements, with semantic transitions across many scales. To navigate through this large, two-dimensional abstraction map we highlight locations that users frequently visit for certain tasks and datasets. Particularly interesting viewpoints can be explicitly saved to optimize the workflow. We have developed DimSUM together with domain scientists specialized in DNA nanotechnology. In the paper we discuss our design decisions for both the visualization and the interaction techniques. We demonstrate two practical use cases in which our approach increases the specialists’ understanding and improves their effectiveness in the analysis. Finally, we discuss the implications of our concept for the use of controlled abstraction in visualization in general.

Original languageEnglish (US)
Pages (from-to)403-413
Number of pages11
JournalComputer Graphics Forum
Volume37
Issue number3
DOIs
StatePublished - Jun 2018
Externally publishedYes

Bibliographical note

Funding Information:
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 686647. This work was also partially funded under the ILLUSTRARE grant by FWF (I 2953-N31), ANR (ANR-16-CE91-0011-01), and the WWTF (VRG11-010). This paper was partly written in collaboration with the VRVis Competence Center. VRVis is funded by BMVIT, BMWFW, Styria, SFG and Vienna Business Agency in the scope of COMET - Competence Centers for Excellent Technologies (854174) which is managed by FFG. We thank Yasaman Ahmadi and Tadija Kekic for providing valuable input to this work and also David Kouril who created the submission video.

Publisher Copyright:
© 2018 The Author(s) Computer Graphics Forum © 2018 The Eurographics Association and John Wiley & Sons Ltd. Published by John Wiley & Sons Ltd.

Keywords

  • Applied computing → Computational biology
  • CCS Concepts
  • Human-centered computing → Scientific visualization
  • Visualization theory, concepts and paradigms

ASJC Scopus subject areas

  • Computer Graphics and Computer-Aided Design

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