Diagnostic and therapeutic applications of smart nanocomposite dendrimers

Vinay Kumar, Rakesh K. Sahoo, Trambak Basak, Tanjina Yasmin, Umesh Gupta, Amit K. Goyal

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Dendrimers are three dimensional, multifunctional polymeric structures which are composed of a core and branches emanating from these structures, resembling a tree. Here, we review the key highlights of the dendrimers for diagnostic uses as MRI contrast agents, X-ray computed tomography and particularly for cancer treatment as an effective carrier for drug delivery and in boron capture therapy. We will discuss how dendrimers represent a new class of carriers that are able to deliver drugs effectively and in a sustained manner to the target tumor sites. Dendrimers are being utilized to a variety of cancer therapies to improve the safety and effectiveness of anticancer therapeutics. This review will also investigates the benefits utilizing dendrimers for cancer diagnosis and therapy.
Original languageEnglish (US)
Pages (from-to)518-536
Number of pages19
JournalFrontiers in Bioscience - Landmark
Volume26
Issue number3
DOIs
StatePublished - Jan 1 2021
Externally publishedYes

Bibliographical note

Generated from Scopus record by KAUST IRTS on 2023-10-12

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