Design and synthesis of macroporous polymeric separation media based on substituted phenols

Wesley Rolls, Frantisek Svec, Jean M.J. Fréchet*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


The suspension copolymerization of several t-butoxycarbonyl (t-BOC) protected 4-vinyl phenols with divinylbenzene has been studied to produce high porosity 10 μm bead materials with surface areas of 200-300 m2/g for use as separation media. The choice and amount of porogen is critical for the control of porosity and surface area while particle size and size distribution is controlled by other reaction variables. The t-BOC protecting groups of the polymers are easily removed by thermolysis and the deprotected beads are useful in the separation of amines. The relationship between polymer structure and separation ability in h.p.l.c. has been explored and the effect of alkyl substituents located ortho to the phenolic groups is discussed.

Original languageEnglish (US)
Pages (from-to)165-174
Number of pages10
Issue number1
StatePublished - Jan 1990
Externally publishedYes

Bibliographical note

Funding Information:
Financial support of this work from the Natural Sciences and Engineering Research Council of Canada and from IBM Corporation's Materials and Processing Sciences Program is gratefully acknowledged. The authors also wish to thank Dr Daniel Horak for valuable discussions and assistance in performing size, surface area, and porosity measurements.


  • macroporous poly(vinylphenol)
  • porogen
  • separation media
  • suspension polymerization

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry


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