Abstract
The National Genomics Data Center (NGDC), part of the China National Center for Bioinformation (CNCB), provides a family of database resources to support global research in both academia and industry. With the explosively accumulated multi-omics data at ever-faster rates, CNCB-NGDC is constantly scaling up and updating its core database resources through big data archive, curation, integration and analysis. In the past year, efforts have been made to synthesize the growing data and knowledge, particularly in single-cell omics and precision medicine research, and a series of resources have been newly developed, updated and enhanced. Moreover, CNCB-NGDC has continued to daily update SARS-CoV-2 genome sequences, variants, haplotypes and literature. Particularly, OpenLB, an open library of bioscience, has been established by providing easy and open access to a substantial number of abstract texts from PubMed, bioRxiv and medRxiv. In addition, Database Commons is significantly updated by cataloguing a full list of global databases, and BLAST tools are newly deployed to provide online sequence search services.
Original language | English (US) |
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Pages (from-to) | D27-D38 |
Number of pages | 1 |
Journal | Nucleic acids research |
Volume | 50 |
Issue number | D1 |
DOIs | |
State | Published - Oct 28 2021 |
Externally published | Yes |
Bibliographical note
KAUST Repository Item: Exported on 2022-05-25Acknowledged KAUST grant number(s): FCC/1/1976–18-01, FCC/1/1976–23-01, FCC/1/1976–25-01, FCC/1/1976–26-01, REI/1/0018–01-01, REI/1/4216–01-01, REI/1/4437–01-01, REI/1/4473–01-01, URF/1/4352–01-01, URF/1/4379–01-01, REI/1/4742–01-01, URF/1/4098–01-01
Acknowledgements: Strategic Priority Research Program of the Chinese Academy of Sciences [XDB38030200, XDB38050300, XDB38030400, XDA19050302, XDA19090116, XDA24040201, XDB38030100, XDA12030100, XDB38040300]; National Key Research and Development Program of China [2019YFA0801801, 2018YFA0801405, 2018YFD1000505, 2018YFC2000100, 2018YFC1406902, 2018YFC0910400, 2018YFC0310602, 2018YFA0903700, 2018YFA0900704, 2017YFC1201200, 2017YFC0908405, 2017YFC0908404, 2017YFC0908403, 2017YFC0907505, 2017YFC0907503, 2017YFC0907502, 2016YFE0206600, 2016YFC0906403, 2016YFC0903003, 2016YFC0901904, 2016YFC0901903, 2016YFC0901702, 2016YFC0901604, 2016YFC0901603, 2016YFB0201702, 2016YFA0501704, 2021YFC0863300, 2016YFC0902500, 2018YFA0900700]; National Natural Science Foundation of China [91731303, 81670462, 31970565, 31871328, 31871294, 31701117, 31970647, 21621004, 31801104, 31771465, 31771410, 31771388, 31671360, 81701567, 31571358, 31525014, 1470330, 31961130380, 31711530221, 31771477, 31571366, 31822030, 31801113, 31801154, 31771458, 91940303, 91940306, 31661143031, 31730110, 31871281, 31970634, 31930021, 32025009, 31970633, 32100520, 62002388, 61772557, 81761168038, 82161148009]; International Partnership Program of the Chinese Academy of Sciences [153F11KYSB20160008, 153D31KYSB20170121]; 13th Five-year Informatization Plan of Chinese Academy of Sciences [XXH13505-05]; Genomics Data Center Construction of Chinese Academy of Sciences [WX145XQ07-04]; Fundamental Research Funds for the Central Universities [2019kfyRCPY043]; UK Royal Society-Newton Advanced Fellowship [NAF\R1\191094]; Key Program of the Chinese Academy of Sciences [KJZD-EW-L14]; Key Research Program of Frontier Sciences of the Chinese Academy of Sciences [QYZDJ-SSW-SYS009]; Key Technology Talent Program of the Chinese Academy of Sciences; 100 Talent Program of the Chinese Academy of Sciences; K.C. Wong Education Foundation; Youth Innovation Promotion Association of the Chinese Academy of Sciences [2019104, 2018134, 2017141]; National Key R&D Program [SQ2017YFSF090210]; China Postdoctoral Science Foundation [2019M652623, 2018M632830]; China 863 Program [2015AA020108]; Open Biodiversity and Health Big Data Program of IUBS; Professional Association of the Alliance of International Science Organizations [ANSO-PA-2020–07]; Funds for Basic Resources Investigation Research of the Ministry of Science and Technology [2018FY10080002]; Special Project on National Science and Technology Basic Resources Investigation [2019FY100102]; CAS Pioneer 100-Talent program; Key Research Program of the Chinese Academy of Sciences [KFZD-SW-219–5]; Zhang jiang special project of national innovation demonstration zone [ZJ2018-ZD-013]; Science and Technology Service Network Initiative of Chinese Academy of Sciences; Hunan Provincial Science and Technology Program [2018wk4001]; 111 Project [B18059]; King Abdullah University of Science and Technology (KAUST) [FCC/1/1976–18-01, FCC/1/1976–23-01, FCC/1/1976–25-01, FCC/1/1976–26-01, REI/1/0018–01-01, REI/1/4216–01-01, REI/1/4437–01-01, REI/1/4473–01-01, URF/1/4352–01-01, URF/1/4379–01-01, REI/1/4742–01-01, URF/1/4098–01-01]; Chinese Academy of Sciences [KFJ-BRP-017–79]. Funding for open access charge: Strategic Priority Research Program of the Chinese Academy of Sciences [XDB38030200].
This publication acknowledges KAUST support, but has no KAUST affiliated authors.
ASJC Scopus subject areas
- Genetics