With advances in sequencing technology, metatranscriptome sequencing from a variety of environmental and biological sources has revealed the existence of various previously unknown RNA viruses. This review presents recent major RNA virome studies sampled from invertebrate and vertebrate species as well as aquatic environments. In particular, we focus on severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and related RNA virus identification through metatranscriptome sequencing analyses. Recently developed bioinformatics software and databases for RNA virus identification are introduced. A relationship between newly identified RNA viruses and endogenous viral elements in host genomes is also discussed.
Bibliographical noteKAUST Repository Item: Exported on 2023-05-19
Acknowledgements: This work was supported by JSPS KAKENHI Grant-in-Aid for Scientific Research (C) 20K06775 (to S.N. and S.S.); Early-Career Scientists 20K15685 and 22K14999 (to S.S.); and Scientific Research on Innovative Areas 16H06429 (to S.N.), 16K21723 (to S.N.), 17H05823 (to S.N.), 19H04843 (to S.N.); by JST CREST (JPMJCR20H6, to S.N.); and by AMED under grant numbers JP21wm0325004 (to S.N.) and 22wm0325004 (to S.N.)
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)