Current nanotechnological strategies for treating glaucoma

Gagandeep Goyal, Tarun Garg, Goutam Rath, Amit K. Goyal

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Glaucoma is a common cause of blindness worldwide, and the development of treatments is difficult for pharmaceutical scientists because successful delivery of drugs to the anterior and posterior segments of eye is challenging due to anatomical and physiological constraints. Conventional treatments use various dosage forms (solutions, suspensions, and ointments) that are hindered by poor intraocular penetration and/or rapid ocular elimination. Therefore, effective, safe, and comfortable methods of drug delivery are needed. One approach to improving ocular therapy is the use of nanotechnology for drug delivery. Recent drug delivery approaches using gels, liposomes, niosomes, ocular inserts, contact lenses, microparticles, nanoparticles, nanosuspensions, and other materials have produced exciting new therapies for ocular diseases, especially glaucoma. In this review, we discuss the importance of nanotechnology in novel drug delivery systems and the future possibilities for an effective treatment of glaucoma. © 2014 Begell House, Inc.
Original languageEnglish (US)
Pages (from-to)365-405
Number of pages41
JournalCritical Reviews in Therapeutic Drug Carrier Systems
Issue number5
StatePublished - Jan 1 2014
Externally publishedYes

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Generated from Scopus record by KAUST IRTS on 2023-10-12


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